Browsing by Author "Clarke, Gerard"

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Browsing by Author "Clarke, Gerard"

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  • Tryptophan degradation in irritable bowel syndrome: evidence of indoleamine 2,3-dioxygenase activation in a male cohort 
    Clarke, Gerard; Fitzgerald, Peter; Cryan, John F.; Cassidy, Eugene M.; Quigley, Eamonn M.; Dinan, Timothy G. (BioMed Central Ltd., 2009-01-20)
    Background: Irritable bowel syndrome (IBS) is a common disorder that affects 10–15% of the population. Although characterised by a lack of reliable biological markers, the disease state is increasingly viewed as a disorder ...
  • Dynamic 5-HT2C receptor editing in a mouse model of obesity 
    Schellekens, Harriët; Clarke, Gerard; Jeffery, Ian B.; Dinan, Timothy G.; Cryan, John F. (PLOS, 2012-03-20)
    The central serotonergic signalling system has been shown to play an important role in appetite control and the regulation of food intake. Serotonin exerts its anorectic effects mainly through the 5-HT1B, 5-HT2C and 5-HT6 ...