Browsing by Author "GlaxoSmithKline"

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Browsing by Author "GlaxoSmithKline"

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  • McKernan, Declan P.; Nolan, Aoife; Brint, Elizabeth K.; O'Mahony, Siobhain M.; Hyland, Niall P.; Cryan, John F.; Dinan, Timothy G. (Public Library of Science, 2009-11-09)
    Background: Irritable bowel syndrome (IBS) is largely viewed as a stress-related disorder caused by aberrant brain-gut– immune communication and altered gastrointestinal (GI) homeostasis. Accumulating evidence demonstrates ...
  • Dennison, Una; McKernan, Declan P.; Cryan, John F.; Dinan, Timothy G. (Cambridge University Press, 2012)
    Background. Increasing evidence indicates that childhood trauma is a risk factor for schizophrenia and patients with this syndrome have a pro-inflammatory phenotype. We tested the hypothesis that the pro-inflammatory ...
  • Murphy, Carola T.; Nally, Kenneth; Shanahan, Fergus; Melgar, Silvia (Hindawi Publishing Corporation, 2012-01)
    Inflammatory bowel disease (IBD), encompassing Crohn's disease and ulcerative colitis, is associated with enhanced leukocyte infiltration to the gut, which is directly linked to the clinical aspects of these disorders. ...