Browsing by Author "van Sinderen, Douwe"

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Browsing by Author "van Sinderen, Douwe"

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  • Lactococcus lactis is capable of improving the riboflavin status in deficient rats 
    LeBlanc, Jean Guy; Burgess, Catherine; Sesma, Fernando; de Giori, Graciela Savoy; van Sinderen, Douwe (Cambridge University Press, 2005)
    Lactococcus lactis is a commonly used starter strain that can be converted from a vitamin B2 consumer into a vitamin B2 'factory' by over-expressing its riboflavin biosynthesis genes. The present study was conducted to ...
  • A genetic dissection of the LlaJI restriction cassette reveals insights on a novel bacteriophage resistance system 
    O'Driscoll, Jonathan; Heiter, Daniel F.; Wilson, Geoffrey G.; Fitzgerald, Gerald F.; Roberts, Richard; van Sinderen, Douwe (BioMed Central, 2006-04-28)
    Background: Restriction/modification systems provide the dual function of protecting host DNA against restriction by methylation of appropriate bases within their recognition sequences, and restriction of foreign invading ...
  • High resolution in vivo bioluminescent imaging for the study of bacterial tumour targeting 
    Cronin, Michelle; Akin, Ali R.; Collins, Sara A.; Meganck, Jeff; Kim, Jae-Beom; Baban, Chwanrow K.; Joyce, Susan A.; van Dam, Gooitzen M.; Zhang, Ning; van Sinderen, Douwe; O’Sullivan, Gerald C.; Kasahara, Noriyuki; Gahan, Cormac G.; Francis, Kevin P.; Tangney, Mark (PLOS, 2012-01-25)
    The ability to track microbes in real time in vivo is of enormous value for preclinical investigations in infectious disease or gene therapy research. Bacteria present an attractive class of vector for cancer therapy, ...