Browsing by Author "Health Research Board"

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Browsing by Author "Health Research Board"

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  • O’Mahony, David; Murphy, Sharon; Boileau, Thomas; Park, JeanSoon; O'Brien, Frances; Groeger, David; Konieczna, Patrycja; Ziegler, Mario; Scully, Paul; Shanahan, Fergus; Kiely, Barry; O'Mahony, Liam (BioMed Central, 2010-12-22)
    Background: Bifidobacteria and lactobacilli are among the early and important colonizers of the gastrointestinal tract and are generally considered to be part of a normal, healthy microbiota. It is believed that specific ...
  • Geaney, Fiona; Harrington, Janas; Fitzgerald, Anthony P.; Perry, Ivan J. (Cambridge University Press, 2011-01)
    Owing to modern lifestyles, individuals are dependent on out-of-home eating. The catering sector can have a pivotal role in influencing our food choices. The objective of the present study was to examine the impact of a ...
  • O'Boyle, Noel M.; Vandermeersch, Tim; Flynn, Christopher J.; Maguire, Anita R.; Hutchison, Geoffrey R. (Chemistry Central Ltd., 2011-03-16)
    Background: Many computational chemistry analyses require the generation of conformers, either on-the-fly, or in advance. We present Confab, an open source command-line application for the systematic generation of low-energy ...
  • Verdonck, Michèle Claire; McCormack, Cathy; Chard, Gill (College of Occupational Therapists, 2011-04)
    Introduction: Electronic assistive technology (EAT) includes computers, environmental control systems and information technology systems and is widely considered to be an important part of present-day life. Method: ...
  • Verdonck, Michèle Claire; Chard, Gill; Nolan, Maeve (Informa Healthcare, 2011-05)
    Purpose. This study explores the experiences of Irish people with high cervical spinal cord injuries living with electronic aids to daily living (EADL) and the meaning attributed to such systems in the context of participation ...
  • Savage, Eileen; Beirne, Paul V.; Ní Chróinín, Muireann; Duff, Alistair; Fitzgerald, Anthony P.; Farrell, Dawn (John Wiley & Sons, Ltd., 2011-07)
    Self-management education may help patients with cystic fibrosis and their families to choose, monitor and adjust treatment requirements for their illness, and also to manage the effects of illness on their lives. Although ...
  • O'Boyle, Noel M.; Campbell, Casey M.; Hutchinson, Geoffrey R. (American Chemical Society, 2011-08)
    Conjugated organic polymers are key building blocks of low-cost photovoltaic materials. We have examined over 90 000 copolymers using computational predictions to solve the "inverse design" of molecular structures with ...
  • O'Boyle, Noel M.; Banck, Michael; James, Craig A.; Morley, Chris; Vandermeersch, Tim; Hutchison, Geoffrey R. (Chemistry Central, 2011-10-07)
    Background A frequent problem in computational modeling is the interconversion of chemical structures between different formats. While standard interchange formats exist (for example, Chemical Markup Language) and de facto ...
  • O'Boyle, Noel M.; Guha, Rajarshi; Willighagen, Egon L.; Adams, Samuel E.; Alvarsson, Jonathan; Bradley, Jean-Claude; Filippov, Igor V.; Hanson, Robert M.; Hanwell, Marcus D.; Hutchison, Geoffrey R.; James, Craig A James; Jeliazkova, Nina; Lang, Andrew SID; Langner, Karol M.; Lonie, David C.; Lowe, Daniel M.; Pansanel, Jérôme; Pavlov, Dmitry; Spjuth, Ola; Steinbeck, Christoph; Tenderholt, Adam L.; Theisen, Kevin J.; Murray-Rust, Peter (Chemistry Central, 2011-10-14)
    Background The Blue Obelisk movement was established in 2005 as a response to the lack of Open Data, Open Standards and Open Source (ODOSOS) in chemistry. It aims to make it easier to carry out chemistry research by promoting ...
  • Harrington, Janas; Fitzgerald, Anthony P.; Layte, Richard; Lutomski, Jennifer; Molcho, Michal; Perry, Ivan J. (Cambridge University Press, 2011-12)
    Objective Poor-quality diet, regarded as an important contributor to health inequalities, is linked to adverse health outcomes. We investigated sociodemographic and lifestyle predictors of poor-quality diet in a population ...
  • Miller, Anne-Marie; Deighan, Brian F.; Downer, Eric; Lyons, Anthony; Henric-Noak, Petra; Nolan, Yvonne M.; Lynch, Marina A. (InTech, 2011-12)
    Neuroinflammation, accompanied by neuronal loss and dysfunction, is a characteristic of neurodegenerative disorders like Alzheimer’s disease (AD) and Parkinson’s disease (PD). It is well documented that inappropriate ...
  • Cronin, Michelle; Akin, Ali R.; Collins, Sara A.; Meganck, Jeff; Kim, Jae-Beom; Baban, Chwanrow K.; Joyce, Susan A.; van Dam, Gooitzen M.; Zhang, Ning; van Sinderen, Douwe; O’Sullivan, Gerald C.; Kasahara, Noriyuki; Gahan, Cormac G.; Francis, Kevin P.; Tangney, Mark (PLOS, 2012-01-25)
    The ability to track microbes in real time in vivo is of enormous value for preclinical investigations in infectious disease or gene therapy research. Bacteria present an attractive class of vector for cancer therapy, ...
  • Eccles, Kevin S.; Morrison, Robin; Stokes, Stephen P.; O'Mahony, Graham E.; Hayes, John; Kelly, Dawn M.; O'Boyle, Noel M.; Fábián, László; Moynihan, Humphrey A.; Maguire, Anita R.; Lawrence, Simon E. (American Chemical Society, 2012-05)
    The propensity of a range of different sulfoxides and sulfones to cocrystallize with either 1,2- or 1,4-diiodotetrafluorobenzene, via I•••O=S halogen bonding, was investigated. Cocrystallization occurred exclusively ...
  • Verdonck, Michèle Claire (University College Cork, 2012-05)
    Environmental Control Systems (ECS), enable people with high cervical Spinal Cord Injury (high SCI) to control and access everyday electronic devices. In Ireland, however, access for those who might benefit from ECS is ...
  • Landers, Margaret; McCarthy, Geraldine; Savage, Eileen (Sage Publications, 2012-05)
    Aim: The purpose of this paper is to present some of the challenges found to be problematic in recruiting individuals following sphincter saving surgery for rectal cancer for a multicentre study. While the focus of the ...
  • Landers, Margaret; McCarthy, Geraldine; Savage, Eileen (Elsevier, 2012-07)
    The aim of this research was to explore participants’ qualitative perspectives on bowel symptom experiences and management strategies following sphincter saving surgery for rectal cancer. Methods and sample The data presented ...
  • O'Driscoll, Adam (University College Cork, 2012-10)
    Crohn's Disease (CD) is a chronic inflammatory bowel disease of unknown etiology. Recent work has shown that a new pathotype of Escherichia coli, Adherent Invasive E. coli (AIEC) may be associated with CD. AIEC has been ...
  • Daly, Carla A.; Eccles, Kevin S.; Bateman, Lorraine M.; O'Boyle, Noel M.; Lawrence, Simon E.; Maguire, Anita R. (Royal Society of Chemistry, 2012-12)
    Design, synthesis and structural characterization of a series of diphenylacetylene derivatives bearing organosulfur, amide and amine moieties has been achieved in which the molecular conformation is controlled through ...
  • Goulding, Niamh E. (University College Cork, 2013)
    Renal failure (RF) is associated with an over activation of the sympathetic nervous system. The aim of this thesis was to investigate the hypothesis that as the kidney progresses into RF there is an inappropriate and ...
  • Byrne, William L. (University College Cork, 2013)
    Cancer represents a leading of cause of death in the developed world, inflicting tremendous suffering and plundering billions from health budgets. The traditional treatment approaches of surgery, radiotherapy and chemotherapy ...