Continuous non-destructive monitoring of cell health using impedance based interdigitated electrode structured sensors

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Date
2011-06-10
Authors
Paschero, Anna
McLoughlin, Eve
Moore, Eric J.
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American Institute of Physics
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Abstract
This article examines some preliminary tests which were performed in order to evaluate the best electrode configuration (width and spacing) for cell culture analyses. Biochips packaged with indium tin oxide (ITO) interdigitated electrodes (IDEs) were used to perform impedance measurements on A549 cells cultured on the surface of the biochip. Several tests were carried out using a 10 mM solution of Sodium Chloride (NaCl), cell medium and the cell culture itself to characterize some of the configurations already fabricated in the facilities at Tyndall National Institute.
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Keywords
Biochemistry , Cellular biophysics , Optimisation , Electrochemical electrodes
Citation
PASCHERO, A., MCLOUGHLIN, E. & MOORE, E. J. CONTINUOUS NON-DESTRUCTIVE MONITORING OF CELL HEALTH USING IMPEDANCE BASED INTERDIGITATED ELECTRODE STRUCTURED SENSORS, 2011. In Tarasenko, O. ed., BIOLOGY, NANOTECHNOLOGY, TOXICOLOGY, AND APPLICATIONS: Proceedings of the 5th BioNanoTox and Applications International Research Conference, Little Rock, Arkansas, 4–5 November 2010. AIP, pp. 100-105.
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©2011 American Institute of Physics