Microbial diversity in the human intestine and novel insights from metagenomics

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dc.contributor.authorVentura, Marco
dc.contributor.authorTurroni, Francesca
dc.contributor.authorCanchaya, Carlos
dc.contributor.authorVaughan, Elaine E.
dc.contributor.authorO'Toole, Paul W.
dc.contributor.authorvan Sinderen, Douwe
dc.contributor.funderScience Foundation Irelanden
dc.contributor.funderDepartment of Agriculture and Food, Irelanden
dc.contributor.funderMinistero dell’Istruzione, dell’Università e della Ricerca, Italyit
dc.contributor.funderParmalat SpA, Italyen
dc.contributor.funderEuropean Commissionen
dc.date.accessioned2010-02-15T13:39:18Z
dc.date.available2010-02-15T13:39:18Z
dc.date.copyright2009
dc.date.issued2009-01-01
dc.date.updated2010-02-15T12:52:27Z
dc.description.abstractBacterial communities reside in very different ecological niches on and within the human host, such as those associated with the alimentary tract. The human gastrointestinal tract is populated with as many as 100 trillion bacterial cells, whose collective genome likely reflects the co-evolution between the microbial community and its host. Recent progress has highlighted the intriguing diversity of these bacterial populations and their important contributions to human physiology. Thus, a thorough understanding of the autochthonous component of the intestinal microbiota is expected to provide crucial information not only on how to develop therapies for various gastrointestinal diseases but also on how to choose the next generation of probiotic bacteria as part of novel functional foods. Recently, novel culture-independent approaches such as metagenomics-based techniques were shown to be crucially important for the exploration of the biodiversity of the human intestinal microbiota.en
dc.description.sponsorshipScience Foundation Ireland; Department of Agriculture and Food, Ireland (FHRI award); Ministero dell’Istruzione, dell’Università e della Ricerca, Italy (Italian Award for Outstanding Young Researcher scheme "Incentivazione alla mobilita’ di studiosi stranieri e italiani residenti all’estero"); European Commission (Marie Curie Reintegration Grant MERG-CT-2005-03080); Parmalat SpA, Italyen
dc.description.statusPeer revieweden
dc.description.versionAccepted Versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.citationVentura, M, Turroni, F, Canchaya, C, Vaughan, EE, O'Toole, PW, van Sinderen, D (2009) 'Microbial Diversity In The Human Intestine and Novel Insights From Metagenomics'. Frontiers In Bioscience, 14 (1):3214-3863.en
dc.identifier.doi10.2741/3445
dc.identifier.endpage3221en
dc.identifier.issn1093-9946
dc.identifier.issn1093-4715
dc.identifier.issued1en
dc.identifier.journaltitleFrontiers In Bioscienceen
dc.identifier.startpage3214en
dc.identifier.urihttps://hdl.handle.net/10468/117
dc.identifier.volume14en
dc.language.isoenen
dc.publisherFrontiers In Bioscienceen
dc.rights© Frontiers in Bioscienceen
dc.subjectIntestinal microbiotaen
dc.subjectMetagenomicsen
dc.subjectNovel probioticen
dc.subjectProbiotic bacteriaen
dc.subject.lcshGastrointestinal system -- Microbiologyen
dc.subject.meshGenome, Bacterialen
dc.titleMicrobial diversity in the human intestine and novel insights from metagenomicsen
dc.typeArticle (peer-reviewed)en
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