INFANT A research centre focused entirely on pregnancy, birth and early childhood. Hosted at University College Cork (UCC), Cork, Ireland, The Irish Centre for Maternal and Child Health Research has local impact with a global reach. INFANT is answering the international need for research and innovation to improve health outcomes for mothers and babies. Across pregnancy, birth, infancy and childhood, INFANT is solving challenges through its key research themes
(Dove Medical Press, 2014-08-05) McCarthy, Fergus P.; Lutomski, Jennifer E.; Greene, Richard A.
Hyperemesis gravidarum is a complex condition with a multifactorial etiology characterized by severe intractable nausea and vomiting. Despite a high prevalence, studies exploring underlying etiology and treatments are limited. We performed a literature review, focusing on articles published over the last 10 years, to examine current perspectives and recent developments in hyperemesis gravidarum.
(Elsevier, 2018-03-10) Hayes-Ryan, Deirdre; McCarthy, Fergus P.; O'Donoghue, Keelin; Kenny, Louise C.
Placental growth factor is an angiogenic protein, highly expressed during pregnancy, which correlates well with placental function. In this review, we highlight the origin, structure and function of Placental Growth Factor and its receptors. We discuss how their pro-angiogenic/anti-angiogenic synergism is critical for successful placentation and how their imbalance may be utilised as a diagnostic marker of disease or a potential therapeutic target for adverse pregnancy outcomes.