Tyndall National Institute - Conference Items
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- ItemDetermination of physical parameters for HfO 2/SiO x/TiN MOSFET gate stacks by electrical characterization and reverse modeling(Institute of Electrical and Electronics Engineers (IEEE), 2008-05-23) Monaghan, Scott; Hurley, Paul K.; Cherkaoui, Karim; Negara, Muhammad Adi; Schenk, A.; Sixth Framework Programme; Science Foundation Ireland; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen ForschungIn this paper we present the results of a combined electrical and modeling study to determine the tunneling electron effective mass and electron affinity for HfO 2 . Experimental capacitance-voltage (C-V) and current-voltage (I-V) characteristics are presented for HfO 2 films deposited on Si(100) substrates by atomic layer deposition (ALD) and electron beam evaporation (e-beam), with equivalent oxide thickness in the range 10 and 12.5A. We extend on previous studies by applying a self-consistent 1D- Schrodinger-Poisson solver to the entire gate stack, including the inter-layer SiO x region and to the adjacent substrate for non-local barrier tunneling self- consistently linked to the quantum-drift-diffusion transport model. The reverse modeling is applied to the correlated gate and drain currents in long channel MOSFET structures. Values of 0.11 + (0.03) m o and 2.0 + (0.25) eV were determined for the HfO 2 electron effective mass and electron affinity.
- ItemNon-invasive multimodal spectroscopic diagnosis for early-stage oral cancer(Optica Publishing Group, 2023) Maryam, Siddra; Ghauri, Daniyal; Sekar, Sanathana Konugolu Venkata; Fahy, Edward; Saito Nogueira, Marcelo; Lu , Huihui; Beffara, Flavien; Humbert, Georges; Burke, Ray; Feeley, Linda; Sheahan, Patrick; Ni Riordain, Richeal; Andersson-Engels, Stefan; Wei Kho, Kiang; Gautam, Rekha; 2023This study aims to develop a multimodal scheme for diagnosing oral cancer non-invasively in its early stages and to assess the performance of an integrated diagnostic platform comprising of Raman and diffuse reflectance spectroscopy systems.
- ItemMulti-configuration Raman spectrometer for early stage diagnosis of oral cancer(Society of Photo-Optical Instrumentation Engineers (SPIE), 2022-03-02) Maryam, Siddra; Saito Nogueira, Marcelo; Krishna Moorthy, Shree; Sekar, Sanathana Konugolu Venkata ; Lu, Huihui; Gautam, Rekha; Burke, Ray; Andersson-Engels, Stefan; Ni Riordain, Richeal; Sheahan, Patrick; Huang, Zhiwei; Science Foundation IrelandOral Squamous Cell carcinoma (OSCC) is one of the most common and aggressive oral malignancies. Despite all significant advances in medicine, five-year survival rate is still 40%-60%. Diagnosis in early stages is critical as it can improve the survival rate and the quality of life after treatment. This study aims to develop a strategy for diagnosing oral cancer non-invasively in the early stages and to provide better surgical guidance by differentiating healthy and tumor tissues by using Raman spectroscopy. For this purpose, a multimodal Raman system is developed to detect oral cancer biomarkers in patient’s saliva specimen and to study different tissue types in oral cavity with Raman spectroscopy. The developed system is quite compact, easy to use and portable. It can be easily modified for in vivo and ex vivo analysis and can work in both reflection and transmission mode in case of ex vivo measurements. This paper compares the surface enhancement and background spectra from different plasmonic nanoparticles. Lastly, bovine serum albumin (BSA) and uric acid were used as model analytes to at physiologically relevant concentrations to test the performance of the system.
- ItemMultimodal optical spectroscopic approach to design a complete protocol for early diagnosis of oral cancer(Society of Photo-Optical Instrumentation Engineers (SPIE), 2023-03-06) Maryam, Siddra; Ghauri, M. Daniyal; Fahy, Edward; Sekar, Sanathana Konugolu Venkata; Lu, Huihui; Russo, Alida; Saito Nogueira, Marcelo; Burke, Ray; Feeley, Linda; Sheahen, Patrick; Ni Riordain, Richeal; Andersson-Engels, Stefan; Kho, Kiang Wei; Gautam, Rekha; Boudoux, Caroline; Tunnell, James W.; Science Foundation IrelandOral cancer is one of the most malignant cancers in the world. Early-stage diagnosis of oral cancer is complex process due to the multifocal unspecific development of non-malignant lesions into cancer and impossibility to take biopsy of every lesion. The aim of this study is to develop a screening method for oral cancer diagnosis at early stages using surface enhanced Raman spectroscopy (SERS) and validate the performance of a multimodal system including Raman spectroscopic (RS) and diffuse reflectance spectroscopy (DRS) oral cancer diagnosis and accurate margin detection. The study will involve the identification and integration of spectral biomarkers involved in the carcinogenesis process from different modalities. Each modality SERS, RS and DRS is calibrated and standardized individually. Patients suffering from oral squamous cell carcinoma and other malignant diseases going through biopsy or histopathological examination are enrolled in this study. Ex vivo study involves the SERS analysis of saliva specimen and in vivo analysis will involve measurements on various tissue types, including malignant tissue and healthy contralateral site to evaluate the reproducibility and signal-to-noise ratio using fiber-optic probes for Raman and DRS systems. Feature selection methods and further machine learning tools will be used to discriminate between healthy, benign and cancer lesions based on spectral information and to identify important biomarkers. After data collection, clinician will perform a normal biopsy procedure and histopathological analysis, which will serve as gold standard to determine the sensitivity and specificity of the spectroscopy techniques.
- ItemA programmable Ethernet transport Packetponder using common compact form factor pluggable tunable transceivers to support novel DWDM architectures(Optica Publishing Group, 2023) Raulin, Julie; Davey, Gawen; Verbishchuk, Yuliya; Jeffries, Alexander; Sreenan, Cormac J.; Garcia Gunning, Fatima C.; Science Foundation IrelandWe introduce a packetponder comprising a programmable packet switch with P4 ASIC containing a mixture of “grey” and tunable DWDM pluggable transceivers that, combined with ROADMs, introduces novel possibilities for Ethernet transport architectures.