Preparation and characterisation of solid state forms of paracetamol-O-glucuronide

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dc.contributor.author Hayes, John A.
dc.contributor.author Eccles, Kevin S.
dc.contributor.author Lawrence, Simon E.
dc.contributor.author Moynihan, Humphrey A.
dc.date.accessioned 2013-03-07T11:24:01Z
dc.date.available 2013-03-07T11:24:01Z
dc.date.issued 2012
dc.identifier.citation John A. Hayes, Kevin S. Eccles, Simon E. Lawrence, Humphrey A. Moynihan (2012) 'Preparation and characterisation of solid state forms of paracetamol-O-glucuronide'. Carbohydrate Research, 349 :108-112. http://dx.doi.org/10.1016/j.carres.2011.12.018 en
dc.identifier.volume 349 en
dc.identifier.startpage 108 en
dc.identifier.endpage 112 en
dc.identifier.issn 0008-6215
dc.identifier.uri http://hdl.handle.net/10468/1018
dc.identifier.doi 10.1016/j.carres.2011.12.018
dc.description.abstract The synthesis and crystallisation of the pharmaceutically important metabolite, paracetamol-O-glucuronide, is described. Hydrated and anhydrous forms of the target molecule have been characterised by PXRD, DSC and TGA. In addition, a methanol solvate has been analysed, including single crystal analysis, which represents the first structure solution for this system. en
dc.description.sponsorship Science Foundation Ireland (07/SRC/B1158); Science Foundation Ireland (05/PICA/B802/EC07) en
dc.format.mimetype application/pdf en
dc.language.iso en en
dc.publisher Elsevier en
dc.relation.uri http://www.sciencedirect.com/science/article/pii/S0008621511006136
dc.rights Copyright © 2012, Elsevier. NOTICE: this is the author’s version of a work that was accepted for publication in Carbohydrate Research. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Carbohydrate Research [349, 15 February 2012, 108–112] http://dx.doi.org/10.1016/j.carres.2011.12.018 en
dc.subject Paracetamol-O-glucuronide en
dc.subject Solvates en
dc.subject Hydrates en
dc.subject X-ray diffraction en
dc.title Preparation and characterisation of solid state forms of paracetamol-O-glucuronide en
dc.type Article (peer-reviewed) en
dc.internal.authorurl http://research.ucc.ie/profiles/D004/hmoynihan en
dc.internal.authorcontactother Humphrey Moynihan, Chemistry, University College Cork, Cork, Ireland. +353-21-490-3000 Email: h.moynihan@ucc.ie en
dc.internal.availability Full text available en
dc.date.updated 2013-03-06T17:54:51Z
dc.description.version Accepted Version en
dc.internal.rssid 174607101
dc.contributor.funder Science Foundation Ireland en
dc.description.status Peer reviewed en
dc.identifier.journaltitle Carbohydrate Research en
dc.internal.copyrightchecked No. CORA - ROMEO and Elsevier article posting policies Elsevier AV and set statement en
dc.internal.licenseacceptance Yes en
dc.internal.IRISemailaddress h.moynihan@ucc.ie en
dc.internal.IRISemailaddress simon.lawrence@ucc.ie en


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