Synthesis and Solid State Pharmaceutical Centre (SSPC)

Synthesis and Solid State Pharmaceutical Centre (SSPC)

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  • Carr, Clodagh M.; Rodrigues de Oliveira, Bruno Francesco; Jackson, Stephen A.; Laport, Marinella Silva; Clarke, David J.; Dobson, Alan D. W. (Frontiers Media S.A., 2022-04-12)
    Many marine bacteria produce extracellular enzymes that degrade complex molecules to facilitate their growth in environmental conditions that are often harsh and low in nutrients. Marine bacteria, including those inhabiting ...
  • Gavin, Declan P.; Reen, F. Jerry; Rocha-Martin, J.; Abreu-Castilla, I.; Woods, David F.; Foley, Aoife M.; Sanchez-Murcia, P. A.; Schwarz, Maria; O'Neill, P.; Maguire, Anita R.; O'Gara, Fergal (Springer Nature Switzerland AG, 2019-12-30)
    Microbial enzymes from pristine niches can potentially deliver disruptive opportunities in synthetic routes to Active Pharmaceutical Ingredients and intermediates in the Pharmaceutical Industry. Advances in green chemistry ...
  • Queiroz, Ana Luiza P.; Kerins, Brian M.; Yadav, Jayprakash; Farag, Fatma; Faisal, Waleed; Crowley, Mary Ellen; Lawrence, Simon E.; Moynihan, Humphrey A.; Healy, Anne Marie; Vucen, Sonja; Crean, Abina M. (Springer Nature Switzerland AG, 2021-07-27)
    Microcrystalline cellulose (MCC) is a semi-crystalline material with inherent variable crystallinity due to raw material source and variable manufacturing conditions. MCC crystallinity variability can result in downstream ...
  • Stokes, Stephen P. (University College Cork, 2021-07-20)
    The work presented in this dissertation focuses on the molecular features of small molecules and their interactions with pharmaceutically relevant molecules. Emphasis is placed on cocrystallisation; a method that facilitates ...
  • Crowley, Daniel C.; Brouder, Thomas A.; Kearney, Aoife M.; Lynch, Denis; Ford, Alan; Collins, Stuart G.; Maguire, Anita R. (American Chemical Society, 2021-08-11)
    Generation and use of triflyl azide in flow enables efficient synthesis of a range of α-diazocarbonyl compounds, including α-diazoketones, α-diazoamides, and an α-diazosulfonyl ester, via both Regitz-type diazo transfer ...

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