Synthesis and Solid State Pharmaceutical Centre (SSPC)

Synthesis and Solid State Pharmaceutical Centre (SSPC)

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  • Hickey, Aobha (University College Cork, 2022)
    Quorum sensing (QS) is a complex form of communication employed by bacterial species to coordinate group behaviours through the biosynthesis, secretion and detection of small molecules known as autoinducers (AIs). Understanding ...
  • Carr, Clodagh M.; Rodrigues de Oliveira, Bruno Francesco; Jackson, Stephen A.; Laport, Marinella Silva; Clarke, David J.; Dobson, Alan D. W. (Frontiers Media S.A., 2022-04-12)
    Many marine bacteria produce extracellular enzymes that degrade complex molecules to facilitate their growth in environmental conditions that are often harsh and low in nutrients. Marine bacteria, including those inhabiting ...
  • Gavin, Declan P.; Reen, F. Jerry; Rocha-Martin, J.; Abreu-Castilla, I.; Woods, David F.; Foley, Aoife M.; Sanchez-Murcia, P. A.; Schwarz, Maria; O'Neill, P.; Maguire, Anita R.; O'Gara, Fergal (Springer Nature Switzerland AG, 2019-12-30)
    Microbial enzymes from pristine niches can potentially deliver disruptive opportunities in synthetic routes to Active Pharmaceutical Ingredients and intermediates in the Pharmaceutical Industry. Advances in green chemistry ...
  • Queiroz, Ana Luiza P.; Kerins, Brian M.; Yadav, Jayprakash; Farag, Fatma; Faisal, Waleed; Crowley, Mary Ellen; Lawrence, Simon E.; Moynihan, Humphrey A.; Healy, Anne Marie; Vucen, Sonja; Crean, Abina M. (Springer Nature Switzerland AG, 2021-07-27)
    Microcrystalline cellulose (MCC) is a semi-crystalline material with inherent variable crystallinity due to raw material source and variable manufacturing conditions. MCC crystallinity variability can result in downstream ...
  • Stokes, Stephen P. (University College Cork, 2021-07-20)
    The work presented in this dissertation focuses on the molecular features of small molecules and their interactions with pharmaceutically relevant molecules. Emphasis is placed on cocrystallisation; a method that facilitates ...

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