• A novel method of microsatellite genotyping-by-sequencing using individual combinatorial barcoding 

  Vartia, Salla; Villanueva-Cañas, José L.; Finarelli, John; Farrell, Edward D.; Collins, Patrick C.; Hughes, Graham M.; Carlsson, Jeanette E. L.; Gauthier, David T.; McGinnity, Philip; Cross, Thomas F.; FitzGerald, Richard D.; Mirimin, Luca; Crispie, Fiona; Cotter, Paul D.; Carlsson, Jens (Royal Society, 2016-01-20)

  This study examines the potential of next-generation sequencing based 'genotyping-by-sequencing' (GBS) of microsatellite loci for rapid and cost-effective genotyping in large-scale population genetic studies. The recovery ...
• The orphan nuclear receptor TLX regulates hippocampal transcriptome changes induced by IL-1β 

  Ó Léime, Ciarán S.; Hoban, Alan E.; Hueston, Cara M.; Stilling, Roman; Moloney, Gerard; Cryan, John F.; Nolan, Yvonne M. (Elsevier, 2018-03-05)

  TLX is an orphan nuclear receptor highly expressed within neural progenitor cells (NPCs) in the hippocampus where is regulates proliferation. Inflammation has been shown to have negative effects on hippocampal function as ...
• Bifidobacterium breve UCC2003 employs multiple transcriptional regulators to control metabolism of particular human milk oligosaccharides 

  James, Kieran; O'Connell Motherway, Mary; Penno, Christophe; O'Brien, Rebecca Louise; van Sinderen, Douwe (American Society for Microbiology, 2018-03-02)

  Bifidobacterial carbohydrate metabolism has been studied in considerable detail for a variety of both plant and human-derived glycans, particularly involving the bifidobacterial prototype Bifidobacterium breve UCC2003. We ...
• A decade of Streptococcus thermophilus phage evolution in an Irish dairy plant 

  Lavelle, Katherine; Murphy, James; Fitzgerald, Brian; Lugli, Gabriele A.; Zomer, Aldert; Neve, Horst; Ventura, Marco; Franz, Charles M.; Cambillau, Christian; van Sinderen, Douwe; Mahony, Jennifer (American Society for Microbiology, 2018-03-09)

  Phages of Streptococcus thermophilus present a major threat to the production of many fermented dairy products. To date, only a handful of studies have assessed the biodiversity of S. thermophilus phages in dairy fermentations. ...
• Rhinoscleroma pathogenesis: the type K3 capsule of Klebsiella rhinoscleromatis is a virulence factor not involved in Mikulicz cells formation 

  Corelli, Barbara; Almeida, Ana S.; Sonego, Fabiane; Castiglia, Virginia; Fevre, Cindy; Brisse, Sylvain; Sansonetti, Philippe J.; Tournebize, Régis (Public Library of Science, 2018)

  Rhinoscleroma is a human specific chronic granulomatous infection of the nose and upper airways caused by the Gram-negative bacterium Klebsiella pneumoniae subsp. rhinoscleromatis. Although considered a rare disease, it ...

View more