• Microbiome Modelling Toolbox 2.0: efficient, tractable modelling of microbiome communities 

  Heinken, Almut; Thiele, Ines (Oxford University Press, 2022-02-14)

  Motivation: Constraint-Based Reconstruction and Analysis (COBRA) is a widely used approach for the interrogation and stratification of microbiome samples, yet applications to large-scale cohorts are hampered by limited ...
• Molecular, biochemical and behavioural evidence for a novel oxytocin receptor and serotonin 2C receptor heterocomplex 

  Chruścicka, Barbara; Cowan, Caitlin S. M.; Wallace Fitzsimons, Shauna E.; Borroto-Escuela, Dasiel O.; Druelle, Clémentine; Stamou, Panagiota; Bergmann, Cristian A.; Dinan, Timothy G.; Slattery, David A.; Fuxe, Kjell; Cryan, John F.; Schellekens, Harriët (Elsevier, 2021-02)

  The complexity of oxytocin-mediated functions is strongly associated with its modulatory effects on other neurotransmission systems, including the serotonin (5-hydroxytryptamine, 5-HT) system. Signalling between oxytocin ...
• Bifidobacterium longum counters the effects of obesity: partial successful translation from rodent to human 

  Schellekens, Harriët; Torres-Fuentes, Cristina; van de Wouw, Marcel; Long-Smith, Caitriona M.; Mitchell, Avery; Strain, Conall R.; Berding, Kirsten; Bastiaanssen, Thomaz F. S.; Rea, Kieran; Golubeva, Anna V.; Arboleya, Silvia; Verpaalen, Mathieu; Pusceddu, Matteo M.; Murphy, Amy; Fouhy, Fiona; Murphy, Kiera; Ross, R. Paul; Roy, Bernard L.; Stanton, Catherine; Dinan, Timothy G.; Cryan, John F. (Elsevier B.V., 2021-01)

  The human gut microbiota has emerged as a key factor in the development of obesity. Certain probiotic strains have shown anti-obesity effects. The objective of this study was to investigate whether Bifidobacterium longum ...
• Next-generation food research: Use of meta-omic approaches for characterizing microbial communities along the food chain 

  Yap, Min; Ercolini, Danilo; Álvarez-Ordóñez, Avelino; O'Toole, Paul W.; O'Sullivan, Orla; Cotter, Paul D. (Annual Reviews, 2021-10-22)

  Microorganisms exist along the food chain and impact the quality and safety of foods in both positive and negative ways. Identifying and understanding the behavior of these microbial communities enable the implementation ...
• Bile acids, bioactive signalling molecules in interoceptive gut-to-brain communication 

  Joyce, Susan A.; O'Malley, Dervla (John Wiley & Sons, Inc., 2022-04-12)

  Aside from facilitating solubilisation and absorption of dietary lipids and lipid-soluble vitamins, amphipathic bile acids (BAs) also act as bioactive signalling molecules. A plethora of conjugated or un-conjugated primary ...

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