• The Glucagon-like peptide-1 receptor agonist, exendin-4, ameliorated gastrointestinal dysfunction in the Wistar Kyoto rat model of Irritable Bowel Syndrome 

  O'Brien, Rebecca; O'Malley, Dervla (John Wiley & Sons Ltd., 2019-10-11)

  Background: Glucagon-like peptide-1 (GLP-1) is beneficial in relieving pain-related symptoms of Irritable bowel syndrome (IBS), a prevalent, multi-factorial functional bowel disorder characterized by diarrhea and/or ...
• Regulation of prefrontal cortex myelination by the microbiota 

  Hoban, Alan E.; Stilling, Roman M.; Ryan, Feargal J.; Shanahan, Fergus; Dinan, Ted G.; Claesson, Marcus J.; Clarke, Gerard; Cryan, John F. (Nature Publishing Group, 2016-04-05)

  The prefrontal cortex (PFC) is a key region implicated in a range of neuropsychiatric disorders such as depression, schizophrenia and autism. In parallel, the role of the gut microbiota in contributing to these disorders ...
• MicroRNAs as biomarkers for major depression: A role for let-7b and let-7c 

  Gururajan, Anand; Naughton, Maura; Scott, Karen A.; O'Connor, R. M.; Moloney, Gerard M.; Clarke, Gerard; Dowling, J.; Walsh, A.; Ismail, F.; Shorten, George; Scott, Lucinda V.; McLoughlin, D. M.; Cryan, John F.; Dinan, Ted G. (Nature Publishing Group, 2016-08-02)

  There is a growing emphasis in the field of psychiatry on the need to identify candidate biomarkers to aid in diagnosis and clinical management of depression, particularly with respect to predicting response to specific ...
• Metabolome and microbiome profiling of a stress-sensitive rat model of gut-brain axis dysfunction 

  Bassett, Shalome A.; Young, Wayne; Fraser, Karl; Dalziel, Julie E.; Webster, Jim; Ryan, Leigh; Fitzgerald, Patrick; Stanton, Catherine; Dinan, Timothy G.; Cryan, John F.; Clarke, Gerard; Hyland, Niall; Roy, Nicole C. (Springer Nature, 2019-10-01)

  Stress negatively impacts gut and brain health. Individual differences in response to stress have been linked to genetic and environmental factors and more recently, a role for the gut microbiota in the regulation of ...
• Biodiversity and classification of phages infecting Lactobacillus brevis 

  Feyereisen, Marine; Mahony, Jennifer; Neve, Horst; Franz, Charles M. A. P.; Noben, Jean-Paul; O'Sullivan, Tadhg; Boer, Viktor; van Sinderen, Douwe (Frontiers Media, 2019-10-16)

  Lactobacillus brevis is a lactic acid bacterium that is known as a food and beverage spoilage organism, and more specifically as a beer-spoiler. Phages of L. brevis have been described, but very limited data is available ...

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