Pulmonary embolism and COVID-19

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Date
2020
Authors
Farrell, A. M.
Walsh, L. J.
Plant, Barry J.
Henry, M. T.
Kennedy, Marcus P.
Eustace, Joseph A.
Sadlier, C.
Crowley, M.
Murphy, Desmond M.
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Irish Medical Organisation
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Abstract
Aims: There is increasing concern amongst clinicians of a possible increase in venous thromboembolism (VTE) events in patients with COVID-19. There remains limited data defining the incidence of VTE in this population and thus also a paucity of research examining the impact of targeted treatment in patients with thrombotic complications. Methods: We examined the number of symptomatic VTE events amongst proven COVID-19 patients admitted to a tertiary level academic hospital, over a one-month period. Patient characteristics, admission and discharge inflammatory and coagulation markers were included in the analysis. Results: Sixty-one patients were identified. Twelve patients (19.6%) admitted with COVID-19 were treated for a suspected PE. Of these patients, 3 patients were discharged on anticoagulation, 3 died and 6 remain inpatients at the end of the study period. Discussion: COVID-19 patients are at increased risk of VTE. This risk may extend beyond the period of admission. Further research examining the role of extending the duration of thromboprophylaxis in COVID-19 patients beyond hospital discharge is warranted.
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Keywords
COVID-19 , VTE , Venous thromboembolism , Pulmonary embolus , Anticoagulation
Citation
Farrell, A. M., Walsh, L. J., Plant, B. J., Henry, M. T., Kennedy, M. P., Eustace, J .E., Sadlier, C., Crowley, M. and Murphy, D. M. (2020) 'Pulmonary embolism and COVID-19', Irish Medical Journal, 113(8), P162 (4pp). Available at: https://imj.ie/wp-content/uploads/2020/09/Pulmonary-Embolism-and-COVID-19.pdf (Accessed: 11 December 2020)
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