• Studies in derivatisation and direct arylation of heterocycles 

  Hickey, Aobha (University College Cork, 2022)

  Quorum sensing (QS) is a complex form of communication employed by bacterial species to coordinate group behaviours through the biosynthesis, secretion and detection of small molecules known as autoinducers (AIs). Understanding ...
• Cocrystallising acids and amides: towards pharmaceutical cocrystals 

  Stokes, Stephen P. (University College Cork, 2021-07-20)

  The work presented in this dissertation focuses on the molecular features of small molecules and their interactions with pharmaceutically relevant molecules. Emphasis is placed on cocrystallisation; a method that facilitates ...
• Telescoping of transition metal catalysed and biocatalysed reactions 

  Kelly, Áine (University College Cork, 2020-11-10)

  This thesis describes the telescoping reactions which exploit the diverse catalytic approaches of transition metal catalysis and biocatalysed processes. These processes would normally have conditions that are incompatible. ...
• Telescoping the synthesis and heterogeneous transition metal catalysed asymmetric transformations of α-diazoketones and α-diazoacetamides in continuous flow 

  Crowley, Daniel C. (University College Cork, 2020-09-17)

  This project aims to expand the extensive work carried out by the Maguire group on the synthesis and reactivity of α-diazocarbonyl compounds over the last 25 years, with primary focus on the intramolecular aromatic addition ...
• Development and application of synthetic methodologies based on organosulfur and organophosphorus chemistry 

  Flynn, Aaran J. (University College Cork, 2020-05-22)

  This thesis describes the development and application of synthetic methodologies based on various aspects of organosulfur and organophosphorus chemistry with a focus on understanding the underlying features and synthetic ...

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