Genome-scale analyses of health-promoting bacteria: probiogenomics

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dc.contributor.author Ventura, Marco
dc.contributor.author O'Flaherty, Sarah
dc.contributor.author Claesson, Marcus J.
dc.contributor.author Turroni, Francesca
dc.contributor.author Klaenhammer, Todd R.
dc.contributor.author van Sinderen, Douwe
dc.contributor.author O'Toole, Paul W.
dc.date.accessioned 2010-02-16T10:44:14Z
dc.date.available 2010-02-16T10:44:14Z
dc.date.issued 2009-01
dc.identifier.citation Ventura M., O'Flaherty S., Claesson M. J., Turroni F., Klaenhammer T.R., van Sinderen D., O'Toole P.W. 2009. Genome-scale analyses of health-promoting bacteria: probiogenomics. Nature Reviews Microbiology 7, pp61-71 doi:10.1038/nrmicro2047 en
dc.identifier.volume 7 en
dc.identifier.issued 1 en
dc.identifier.startpage 61 en
dc.identifier.endpage 71 en
dc.identifier.issn 1740-1526
dc.identifier.issn 1740-1534
dc.identifier.uri http://hdl.handle.net/10468/118
dc.identifier.doi 10.1038/nrmicro2047
dc.description.abstract The human body is colonized by an enormous population of bacteria (microbiota) that provides the host with coding capacity and metabolic activities. Among the human gut microbiota are health-promoting indigenous species (probiotic bacteria) that are commonly consumed as live dietary supplements. Recent genomics-based studies (probiogenomics) are starting to provide insights into how probiotic bacteria sense and adapt to the gastrointestinal tract environment. In this Review, we discuss the application of probiogenomics in the elucidation of the molecular basis of probiosis using the well-recognized model probiotic bacteria genera Bifidobacterium and Lactobacillus as examples. en
dc.description.sponsorship Science Foundation Ireland (CSET); Department of Agriculture and Food, Ireland; Health Research Board (FHRI award); Ministero dell’Istruzione, dell’Università e della Ricerca, Italy (Italian Award for Outstanding Young Researcher scheme "Incentivazione alla mobilità di studiosi stranieri e italiani residente all’estero" 2005-2009); European Commission (Marie Curie Reintegration Grant MERG-CT-2005-03080); Parmalat SpA, Italy en
dc.format.mimetype application/pdf
dc.language.iso en en
dc.publisher Nature Publishing Group en
dc.rights © 2009 Macmillan Publishers Limited. All rights reserved en
dc.rights.uri http://www.nature.com/authors/editorial_policies/license.html en
dc.subject Genomics en
dc.subject Functional genomics en
dc.subject Microbiota en
dc.subject Intestinal tract en
dc.subject Probiotic bacteria en
dc.subject.lcsh Bifidobacterium -- Genomics en
dc.subject.lcsh Lactobacillus -- Genomics en
dc.title Genome-scale analyses of health-promoting bacteria: probiogenomics en
dc.type Article (peer-reviewed) en
dc.internal.authorcontactother Douwe van Sinderen, Alimentary Pharmabiotic Centre, University College Cork, Cork. E-mail: d.vansinderen@ucc.ie en
dc.internal.authorcontactother Paul O'Toole, Alimentary Pharmabiotic Centre, University College Cork, Cork. E-mail: pwotoole@ucc.ie en
dc.internal.availability Full text available en
dc.description.version Accepted Version en
dc.internal.rssid 160957278
dc.contributor.funder Science Foundation Ireland en
dc.contributor.funder Health Research Board en
dc.contributor.funder Parmalat SpA, Italy
dc.contributor.funder Department of Agriculture and Food, Ireland en
dc.contributor.funder Ministero dell’Istruzione, dell’Università e della Ricerca, Italy it
dc.contributor.funder European Commission en
dc.description.status Peer reviewed en
dc.identifier.journaltitle Nature Reviews. Microbiology en
dc.internal.IRISemailaddress d.vansinderen@ucc.ie en


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