International comparison of glycaemic control in people with type 1 diabetes: an update and extension

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dc.contributor.author Prigge, R.
dc.contributor.author McKnight, J. A.
dc.contributor.author Wild, S. H.
dc.contributor.author Haynes, A.
dc.contributor.author Jones, T. W.
dc.contributor.author Davis, E. A.
dc.contributor.author Rami-Merhar, B.
dc.contributor.author Fritsch, M.
dc.contributor.author Prchla, Christine
dc.contributor.author Lavens, A.
dc.contributor.author Doggen, K.
dc.contributor.author Chao, S.
dc.contributor.author Aronson, R.
dc.contributor.author Brown, R.
dc.contributor.author Ibfelt, E. H.
dc.contributor.author Svensson, J.
dc.contributor.author Young, R.
dc.contributor.author Warner, J. T.
dc.contributor.author Robinson, H.
dc.contributor.author Laatikainen, T.
dc.contributor.author Rautiainen, P.
dc.contributor.author Delemer, B.
dc.contributor.author Souchon, P. F.
dc.contributor.author Diallo, A. M.
dc.contributor.author Holl, R.W.
dc.contributor.author Schmid, S. M.
dc.contributor.author Raile, K.
dc.contributor.author Tigas, S.
dc.contributor.author Bargiota, A.
dc.contributor.author Zografou, I.
dc.contributor.author Luk, A. O. Y.
dc.contributor.author Chan, J. C. N.
dc.contributor.author Dinneen, S. F.
dc.contributor.author Buckley, Claire M.
dc.contributor.author Kgosidialwa, O.
dc.contributor.author Cherubini, V.
dc.contributor.author Gesuita, R.
dc.contributor.author Strele, I.
dc.contributor.author Pildava, S.
dc.contributor.author Veeze, H.
dc.contributor.author Aanstoot, H.-J.
dc.contributor.author Mul, D.
dc.contributor.author Jefferies, C.
dc.contributor.author Cooper, J. G.
dc.contributor.author Fjeld Løvaas, K.
dc.contributor.author Battelino, T.
dc.contributor.author Dovc, K.
dc.contributor.author Bratina, N.
dc.contributor.author Eeg-Olofsson, K.
dc.contributor.author Svensson, A.-M.
dc.contributor.author Gudbjornsdottir, S.
dc.contributor.author Globa, E.
dc.contributor.author Zelinska, N.
dc.date.accessioned 2021-12-17T10:06:21Z
dc.date.available 2021-12-17T10:06:21Z
dc.date.issued 2021-12-10
dc.identifier.citation Prigge, R., McKnight, J. A., Wild, S. H., Haynes, A., Jones, T. W., Davis, E. A., Rami-Merhar, B., Fritsch, M., Prchla, C., Lavens, A., Doggen, K., Chao, S., Aronson, R., Brown, R., Ibfelt, E. H., Svensson, J., Young, R., Warner, J. T., Robinson, H., Laatikainen, T., Rautiainen, P., Delemer, B., Souchon, P. F., Diallo, A. M. , Holl, R., Schmid, S., Raile, K., Tigas, S., Bargiota, A., Zografou, I., Luk, A. O. Y., Chan, J. C. N., Dinneen, S. F., Buckley, C. M., Kgosidialwa, O., Cherubini, V., Gesuita, R., Strele, I., Pildava, S., Veeze, H., Aanstoot, H.-J., Mul, D., Jefferies, C., Cooper, J. G., Fjeld Løvaas, K., Battelino, T., Dovc, K., Bratina, N., Eeg-Olofsson, K., Svensson, A.-M., Gudbjornsdottir, S., Globa, E. and Zelinska, N. (2021) ‘International comparison of glycaemic control in people with type 1 diabetes: an update and extension’, Diabetic Medicine, e14766. doi: 10.1111/dme.14766 en
dc.identifier.issn 0742-3071
dc.identifier.uri http://hdl.handle.net/10468/12352
dc.identifier.doi 10.1111/dme.14766 en
dc.description.abstract Aims: To update and extend a previous cross-sectional international comparison of glycaemic control in people with type 1 diabetes. Methods: Data were obtained for 520,392 children and adults with type 1 diabetes from 17 population and five clinic-based data sources in countries or regions between 2016 and 2020. Median HbA1c(IQR) and proportions of individuals with HbA1c<58mmol/mol (<7.5%), 58 – 74 mmol/mol (7.5 – 8.9%) and ≥ 75 mmol/mol (≥ 9.0%) were compared between populations for individuals aged <15, 15 – 24 and ≥ 25years. Logistic regression was used to estimate the odds ratio (OR) of HbA1c< 58 mmol/mol (< 7.5%) relative to ≥ 58 mmol/mol (≥ 7.5%), stratified and adjusted for sex, age, and data source. Where possible, changes in the proportion of individuals in each HbA1c category compared to previous estimates were calculated. Results: Median HbA1c varied from 55 to 79 mmol/mol (7.2 to 9.4%) across data sources and age groups so a pooled estimate was deemed inappropriate. OR (95% CI) for HbA1c< 58 mmol/mol (<7.5 %) were 0.91 (0.90 – 0.92) for women compared to men, 1.68 (1.65 – 1.71) for people aged < 15 years and 0.81 (0.79 – 0.82) aged15 – 24 years compared to those aged ≥ 25 years. Differences between populations persisted after adjusting for sex, age, and data source. In general, compared to our previous analysis, the proportion of people with an HbA1c<58 mmol/l (<7.5%) increased and proportions of people with HbA1c≥ 75 mmol/mol (≥ 9.0%) decreased. Conclusions: Glycaemic control of type 1 diabetes continues to vary substantially between age groups and data sources. While some improvement over time has been observed, glycaemic control remains sub-optimal for most people with Type 1 diabetes. en
dc.format.mimetype application/pdf en
dc.language.iso en en
dc.publisher John Wiley & Sons, Inc. en
dc.rights © 2021, John Wiley & Sons Ltd. This is the peer reviewed version of the following item: Prigge, R., McKnight, J. A., Wild, S. H., Haynes, A., Jones, T. W., Davis, E. A., Rami-Merhar, B., Fritsch, M., Prchla, C., Lavens, A., Doggen, K., Chao, S., Aronson, R., Brown, R., Ibfelt, E. H., Svensson, J., Young, R., Warner, J. T., Robinson, H., Laatikainen, T., Rautiainen, P., Delemer, B., Souchon, P. F., Diallo, A. M. , Holl, R., Schmid, S., Raile, K., Tigas, S., Bargiota, A., Zografou, I., Luk, A. O. Y., Chan, J. C. N., Dinneen, S. F., Buckley, C. M., Kgosidialwa, O., Cherubini, V., Gesuita, R., Strele, I., Pildava, S., Veeze, H., Aanstoot, H.-J., Mul, D., Jefferies, C., Cooper, J. G., Fjeld Løvaas, K., Battelino, T., Dovc, K., Bratina, N., Eeg-Olofsson, K., Svensson, A.-M., Gudbjornsdottir, S., Globa, E. and Zelinska, N. (2021) ‘International comparison of glycaemic control in people with type 1 diabetes: an update and extension’, Diabetic Medicine, e14766. doi: 10.1111/dme.14766, which has been published in final form at: https://doi.org/10.1111/dme.14766 This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. en
dc.subject Type 1 diabetes en
dc.subject Glycaemic control en
dc.subject HbA1c en
dc.subject Registers of people with diabetes en
dc.title International comparison of glycaemic control in people with type 1 diabetes: an update and extension en
dc.type Article (peer-reviewed) en
dc.internal.authorcontactother Claire M. Buckley, Public Health, University College Cork, Cork, Ireland. T: +353-21- 490-3000 E: claire.buckley@ucc.ie en
dc.internal.availability Full text available en
dc.check.info Access to this article is restricted until 12 months after publication by request of the publisher. en
dc.check.date 2022-12-10
dc.description.version Accepted Version en
dc.description.status Peer reviewed en
dc.identifier.journaltitle Diabetic Medicine en
dc.internal.IRISemailaddress claire.buckley@ucc.ie en
dc.identifier.articleid e14766 en
dc.internal.bibliocheck In press. Add vol / issue / page numbers. Amend citation and copyright statement as necessary. en
dc.identifier.eissn 1464-5491


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