• Identification of the molecular pathways that mediate cytokine induced immunopathology of the gut epithelium 

  Saini Rokade, Nisha (University College Cork, 2020)

  Although the phenomenon of synergistic cell death induced by the combination of IFN-γ and TNF-α has been known for more than 30 years, the underlying mechanisms are still not clear. The main aim of my PhD was to identify ...
• Encapsulation technologies for delivery of bioactive compounds to the gastrointestinal tract 

  O'Reilly, Catherine (University College Cork, 2021-04-30)

  Ulcerative Colitis and other inflammatory bowel diseases (IBD) are increasingly linked to changes in the gut microbiome. In addition, gastrointestinal illnesses caused by infections by gut pathogens such as Clostridioides ...
• Inflammation driven molecular alterations in disorders of the perinatal brain 

  Casey, Sophie (University College Cork, 2021-03)

  Introduction: Inflammatory insults during the perinatal period are known to disrupt normal neurodevelopmental processes. Neonatal hypoxic ischemic encephalopathy (HIE) may occur with or without infection and is characterised ...
• The microbiome and cancer 

  Barrett, Maurice P. J. (University College Cork, 2021-06-04)

  Cancers arise through the process of somatic evolution fuelled by the inception of somatic mutations. We lack a complete understanding of the sources of these somatic mutations. Humans host a vast repertoire of microbes ...
• The role of health behaviour and lifestyle in immunometabolism and host-microbe interaction 

  Keohane, David M. (University College Cork, 2021-01-01)

  Introduction: Health behaviour relates to a broad category of health directed activities and actions that affect wellbeing and mortality. Health behaviour patterns change rapidly with industrialisation, consequently ...

View more