• The microbiome-gut-brain axis in preclinical alpha-synuclein models of Parkinson's disease 

  O'Donovan, Sarah (University College Cork, 2019)

  Parkinson’s disease (PD) is a progressive irreversible neurodegenerative disorder with no preventative treatment. PD is a multisystem disorder, affecting both central and peripheral nervous systems and is characterised by ...
• An investigation into antimicrobial production in the Lactobacillus genus and the fish microbiome 

  Collins, Fergus W. J. (University College Cork, 2019)

  This thesis outlines a study of the identification and characterisation of antimicrobials from two primary sources; the Lactobacillus genus and the microbiome of fish. Through the incorporation of a wide variety of techniques, ...
• Using high-density mutagenesis to identify the genetic requirements for the growth of Escherichia coli 

  Buttimer, Finbarr James (University College Cork, 2019)

  Escherichia coli is highly adapted to life within the mammalian gastrointestinal (GI) tract, capable of adapting to multiple environments en route to colonising the intestine. Moreover, the means by which the species copes ...
• Investigation of mechanisms underpinning host-microbial interactions in the gastrointestinal tract 

  Udayan, Sreeram (University College Cork, 2019)

  Research in the areas of microbiome science and immunology have identified different members of a host’s microbiota, particularly bacteria, as having critical roles in shaping the development and function of both intestinal ...
• The role of diet in host susceptibility to listeria monocytogenes infection 

  Las Heras, Vanessa (University College Cork, 2019)

  Currently the world is facing an epidemic increase in metabolic disorders linked to the Western-diet, a diet consisting of an increased intake of ready-to-eat food products rich in sugar and animal fat. Diet is a significant ...

View more