Irish SARS-CoV-2 convalescent serological status of children following acute pneumonia during Ireland’s first wave

Irfan, S. Sabir; Flinn, K.; Mullane, David; Murray, Deirdre M.; Linnane, B.; Holder, P.; De Gascun, C.; Ní ­Chróinín, Muireann

Irish SARS-CoV-2 convalescent serological status of children following acute pneumonia during Ireland’s first wave

Files

Irish-SARS-CoV-2-Convalescent-Serological-Status-of-Children-Following-Acute-Pneumonia-During-Irelands-First-Wave.pdf(90.29 KB)

Published version

Date

2022-03

Authors

Irfan, S. Sabir

Flinn, K.

Mullane, David

Murray, Deirdre M.

Linnane, B.

Holder, P.

De Gascun, C.

Ní Chróinín, Muireann

Publisher

Irish Medical Organisation

Abstract

A global epidemic caused by a novel coronavirus (SARS-CoV-2) in China in December 2019 has spread worldwide¹. We hypothesised that due to low levels of viral shedding in children's upper airways, many children with COVID-19 related respiratory illness admitted to the hospital might be negative on nasopharyngeal PCR testing. Evidence suggests that SARS-CoV-2 antibodies can be detected typically 9-14 days after onset of symptoms but may take up to 3 months2. Therefore, convalescent serological evidence of SARS-CoV-2, as an alternative means to determine the rate of COVID-19 infection, was assessed.

Keywords

COVID-19 , Epidemic , Ireland , Children , SARS-CoV-2

Citation

Irfan, S. Sabir, Flinn, K., Mullane, D., Murray, D. M., Linnane, B., Holder, P., De Gascun, C.and Ní Chróinín, M. (2022) 'Irish SARS-CoV-2 convalescent serological status of children following acute pneumonia during Ireland's first wave', Irish Medical Journal, 115 (3), P572 (2 pp).