• Bioaccessibility and bioavailability of a marine-derived multimineral, Aquamin-Magnesium 

  Felice, Valeria D.; O'Gorman, Denise M.; O'Brien, Nora M.; Hyland, Niall P. (MDPI AG, 2018)

  Introduction: Magnesium is an essential mineral involved in a range of key biochemical pathways. Several magnesium supplements are present on the market and their degree of bioavailability differs depending on the form of ...
• Recovery of respiratory function in mdx mice co-treated with neutralizing interleukin-6 receptor antibodies and Urocortin-2 

  Burns, David P.; Canavan, Leonie; Rowland, Jane; O'Flaherty, Robin; Brannock, Molly; Drummond, Sarah E.; O'Malley, Dervla; Edge, Deirdre; O'Halloran, Ken D. (John Wiley & Sons, Inc. on behalf of the Physiological Society, 2018-08-30)

  The mdx mouse model of Duchenne muscular dystrophy shows evidence of hypoventilation and pronounced diaphragm dysfunction. Six‐week‐old male mdx (n = 32) and wild‐type (WT; n = 32) mice received either saline (0.9% w/v) ...
• Functional classification of DNA variants by hybrid minigenes: identification of 30 spliceogenic variants of BRCA2 exons 17 and 18 

  Fraile-Bethencourt, Eugenia; Díez-Gómez, Beatriz; Velásquez-Zapata, Valeria; Acedo, Alberto; Sanz, David J.; Velasco, Eladio A. (Public Library of Science, 2017)

  Mutation screening of the breast cancer genes BRCA1 and BRCA2 identifies a large fraction of variants of uncertain clinical significance (VUS) whose functional and clinical interpretations pose a challenge for genomic ...
• The regulation of monoamine oxidase A gene expression by distinct variable number tandem repeats 

  Manca, Maurizio; Pessoa, Veridiana; Lopez, Ana Illera; Harrison, Patrick T.; Miyajima, Fabio; Sharp, Helen; Pickles, Andrew; Hill, Jonathan; Murgatroyd, Chris; Bubb, Vivien J.; Quinn, John P. (Humana Press, 2018)

  The monoamine oxidase A (MAOA) uVNTR (upstream variable number tandem repeat) is one of the most often cited examples of a gene by environment interaction (GxE) in relation to behavioral traits. However, MAOA possesses a ...
• Sensorimotor control of breathing in the mdx mouse model of Duchenne muscular dystrophy 

  Burns, David P.; Roy, Arijit; Lucking, Eric; McDonald, Fiona B.; Gray, Sam; Wilson, Richard J.; Edge, Deirdre; O'Halloran, Ken D. (John Wiley & Sons, Inc., 2017-09-26)

  Patients with Duchenne muscular dystrophy (DMD) hypoventilate with consequential arterial blood gas derangement relevant to disease progression. Whereas deficits in DMD diaphragm are recognized, there is a paucity of ...

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