• Studies in asymmetric and heterocyclic synthesis: I. chiral ketones II. Quinolones III. Trifluoromethylated pyrones 

  Clarke, Sarah L. (University College Cork, 2015)

  This thesis is split into three sections based on three different areas of research. In the first section, investigations into the α-alkylation of ketones using a novel chiral auxiliary is reported. This chiral auxiliary ...
• New methods for the asymmetric synthesis of α-alkylated ketones and 1,3-amino alcohols 

  McSweeney, Christina M. (University College Cork, 2015)

  A large number of optically active drugs and natural products contain α-functionalised ketones or simple derivatives thereof. Furthermore, chiral α-alkylated ketones are useful synthons and have found widespread use in ...
• Chemoenzymatic routes to enantiopure hydroxytetrahydrofurans: muscarine and its analogues 

  Beecher, Denis (University College Cork, 2015)

  Muscarine was identified as an active principle of the poisonous mushroom Amanita muscaria over 170 years ago and has been identified as an agonist of acetylcholine. The synthesis of all stereoisomers of muscarine have ...
• Organic functionalisation, doping and characterisation of semiconductor surfaces for future CMOS device applications 

  O'Connell, John Joseph (University College Cork, 2016)

  Organic Functionalisation, Doping and Characterisation of Semiconductor Surfaces for Future CMOS Device Applications Semiconductor materials have long been the driving force for the advancement of technology since their ...
• Telescoped approach to aryl hydroxymethylation in the synthesis of a key pharmaceutical intermediate 

  Slattery, Catherine N.; Deasy, Rebecca E.; Maguire, Anita R.; Kopach, Michael E.; Singh, Utpal K.; Argentine, Mark D.; Trankle, William G.; Scherer, Roger B.; Moynihan, Humphrey A. (American Chemical Society, 2013-05-30)

  An efficient synthetic approach leading to introduction of the hydroxymethyl group to an aryl moiety via combination of the Bouveault formylation and hydride reduction has been optimized using a rational, mechanistic-based ...

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