• A novel cold active esterase from a deep sea sponge Stelletta normani metagenomic library 

  Borchert, Erik; Selvin, Joseph; Kiran, Seghal G.; Jackson, Stephen A.; O'Gara, Fergal; Dobson, Alan D. W. (Frontiers Media, 2017)

  Esterases catalyze the hydrolysis of ester bonds in fatty acid esters with short-chain acyl groups. Due to the widespread applications of lipolytic enzymes in various industrial applications, there continues to be an ...
• Identification of secondary metabolite gene clusters in the Pseudovibrio genus reveals encouraging biosynthetic potential toward the production of novel bioactive compounds 

  Naughton, Lynn M.; Romano, Stefano; O'Gara, Fergal; Dobson, Alan D. W. (Frontiers Media S.A., 2017)

  Increased incidences of antimicrobial resistance and the emergence of pan-resistant 'superbugs' have provoked an extreme sense of urgency amongst researchers focusing on the discovery of potentially novel antimicrobial ...
• Biotechnological potential of cold adapted Pseudoalteromonas spp. isolated from "deep sea' sponges 

  Borchert, Erik; Knobloch, Stephen; Dwyer, Emilie; Flynn, Sinead; Jackson, Stephen A.; Johannsson, Ragnar; Marteinsson, Viggo T.; O'Gara, Fergal; Dobson, Alan D. W. (MDPI AG, 2017)

  The marine genus Pseudoalteromonas is known for its versatile biotechnological potential with respect to the production of antimicrobials and enzymes of industrial interest. We have sequenced the genomes of three ...
• Bile signalling promotes chronic respiratory infections and antibiotic tolerance 

  Reen, F. Jerry; Flynn, Stephanie; Woods, David F.; Dunphy, Niall; Ní Chróinín, Muireann; Mullane, David; Stick, Stephen; Adams, Claire; O'Gara, Fergal (Nature Publishing Group, 2016-07-19)

  Despite aggressive antimicrobial therapy, many respiratory pathogens persist in the lung, underpinning the chronic inflammation and eventual lung decline that are characteristic of respiratory disease. Recently, bile acid ...
• Molecular signature of Pseudomonas aeruginosa with simultaneous nanomolar detection of quorum sensing signaling molecules at a Boron-Doped diamond electrode 

  Buzid, Alyah; Shang, Fengjun; Reen, F. Jerry; Ó Muimhneacháin, Eoin; Clarke, Sarah L.; Zhou, Lin; Luong, John H. T.; O'Gara, Fergal; McGlacken, Gerard P.; Glennon, Jeremy D. (Nature Publishing Group, 2016-07-18)

  Electroanalysis was performed using a boron-doped diamond (BDD) electrode for the simultaneous detection of 2-heptyl-3-hydroxy-4-quinolone (PQS), 2-heptyl-4-hydroxyquinoline (HHQ) and pyocyanin (PYO). PQS and its precursor ...

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