• Implementation of transposon mutagenesis in Bifidobacterium 

  Ruiz, Lorena; van Sinderen, Douwe (Humana, New York, NY, 2019-06-14)

  Random transposon mutagenesis allows for relatively rapid, genome-wide surveys to detect genes involved in functional traits, by performing screens of mutant libraries. This approach has been widely applied to identify ...
• Identification of dual receptor binding protein systems in Lactococcal 936 group phages 

  Hayes, Stephen; Duhoo, Yoan; Neve, Horst; Murphy, James; Noben, Jean-Paul; Franz, Charles M. A. P.; Cambillau, Christian; Mahony, Jennifer; Nauta, Arjen; van Sinderen, Douwe (MDPI, 2018)

  Siphoviridae of the lactococcal 936 group are the most commonly encountered bacteriophages in the dairy processing environment. The 936 group phages possess a discrete baseplate at the tip of their tail—a complex harbouring ...
• Long-term colonisation with donor bacteriophages following successful faecal microbial transplantation 

  Draper, Lorraine A.; Ryan, Feargal J.; Smith, Muireann K.; Jalanka, J.; Mattila, E.; Arkkila, P.A.; Ross, R. Paul; Satokari, R.; Hill, Colin (BMC part of Springer Nature, 2018-12-10)

  Faecal microbiota transplantation (FMT) is used in the treatment of recurrent Clostridium difficile infection. Its success is typically attributed to the restoration of a diverse microbiota. Viruses (including bacteriophages) ...
• Biomedical applications for bacteriocins in infection and oncology 

  Ellis, Jenna-Claire (University College Cork, 2018)

  Lantibiotics are a subclass of a group of bacterially produced antimicrobial peptides called bacteriocins. They are characterized by post-translation modifications resulting in the presence of unusual amino acid residues ...
• Bacterial microcompartment-mediated ethanolamine metabolism in E. coli urinary tract infection 

  Dadswell, Katherine; Creagh, Sinead; McCullagh, Edward; Liang, Mingzhi; Brown, Ian R.; Warren, Martin J. McNally, Alan; MacSharry, John; Prentice, Michael B. (American Society for Microbiology, 2019-05-28)

  Urinary tract infections (UTIs) are common, in general caused by intestinal Uropathogenic E. coli (UPEC) ascending via the urethra. Microcompartment-mediated catabolism of ethanolamine, a host cell breakdown product, fuels ...

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