Childhood obesity treatment: integrating mobile health technology into a paediatric obesity service

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dc.contributor.advisor Burls, Amanda en
dc.contributor.advisor Perry, Ivan J. en
dc.contributor.advisor Clarke, Mike en
dc.contributor.author O'Malley, Grace Catherine
dc.date.accessioned 2016-06-23T09:05:00Z
dc.date.issued 2015
dc.date.submitted 2015
dc.identifier.citation O'Malley, G.C. 2015. Childhood obesity treatment: integrating mobile health technology into a paediatric obesity service. PhD Thesis, University College Cork. en
dc.identifier.endpage 231 en
dc.identifier.uri http://hdl.handle.net/10468/2772
dc.description.abstract Background: The management of childhood obesity is challenging. Aims: Thesis, i) reviews the evidence for lifestyle treatment of obesity, ii) explores cardiometabolic burden in childhood obesity, iii) explores whether changes in body composition predicts change in insulin sensitivity (IS), iv) develops and evaluates a lifestyle obesity intervention; v) develops a mobile health application for obesity treatment and vi) tests the application in a clinical trial. Methods: In Study 1, systematic reviews and meta-analyses of the 12‐month effects of lifestyle and mHealth interventions were conducted. In Study 2, the prevalence of cardiometabolic burden was estimated in a consecutive series of 267 children. In Study 3, body composition was estimated with bioelectrical impedance analysis (BIA) and dual x-ray absorptiometry (DXA) and linear regression analyses were used to estimate the extent to which each methods predicted change in IS. Study 4 describes the development of the Temple Street W82GO Healthy Lifestyle intervention for clinical obesity in children and a controlled study of treatment effect in 276 children is reported. Study 5 describes the development and testing of the Reactivate Mobile Obesity Application. Study 6 outlines the development and preliminary report from a clinical effectiveness trial of Reactivate. Results: In Study 1, meta--‐analyses BMI SDS changed by -0.16 (-0.24,‐0.07, p<0.01) and -0.03 (-0.13, 0.06, p=0.48). In study 2, cardiometabolic comorbidities were common (e.g. hypertension in 49%) and prevalence increased as obesity level increased. In Study 3, BC changes significantly predicted changes in IS. In Study 4, BMI SDS was significantly reduced in W82GO compared to controls (p<0.001). In Study 5, the Reactivate application had good usability indices and preliminary 6‐month process report data from Study 6, revealed a promising effect for Reactivate. Conclusions: W82GO and Reactivate are promising forms of treatment. en
dc.description.sponsorship Health Research Board (HPF 2011/54) en
dc.format.mimetype application/pdf en
dc.language.iso en en
dc.publisher University College Cork en
dc.rights © 2015, Grace Catherine O'Malley. en
dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/3.0/ en
dc.subject Obesity en
dc.subject Paediatric en
dc.subject Telemedicine en
dc.subject Smartphone en
dc.subject Mobile health en
dc.subject Behavioural change en
dc.subject Lifestyle intervention en
dc.subject Cardiometabolic risk en
dc.subject mHealth en
dc.title Childhood obesity treatment: integrating mobile health technology into a paediatric obesity service en
dc.type Doctoral thesis en
dc.type.qualificationlevel Practitioner Doctorate en
dc.type.qualificationname PhD (Medicine and Health) en
dc.internal.availability Full text not available en
dc.description.version Accepted Version
dc.contributor.funder Health Research Board en
dc.description.status Not peer reviewed en
dc.internal.school Epidemiology and Public Health en
dc.check.reason This thesis is due for publication or the author is actively seeking to publish this material en
dc.check.opt-out Not applicable en
dc.thesis.opt-out false
dc.check.chapterOfThesis 2,3,5,6
dc.check.embargoformat E-thesis on CORA only en
ucc.workflow.supervisor i.perry@ucc.ie
dc.internal.conferring Summer 2015 en


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© 2015, Grace Catherine O'Malley. Except where otherwise noted, this item's license is described as © 2015, Grace Catherine O'Malley.
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