• Determination of composition distributions of multi-particle crystalline samples by sequential dissolution with concomitant particle sizing and solution analysis 

  Moynihan, Humphrey A.; Armstrong, Declan (Royal Society of Chemistry, 2018-04)

  Impurities arise in the production of molecular pharmaceutical and fine chemical products and are often addressed by crystallisation. However, impurities are not always adequately removed by crystallisations and in some ...
• Cocrystals and a salt of the bioactive flavonoid: naringenin 

  Khandavilli, Udaya Bhaskara Rao; Skořepová, Eliška; Sinha, Abhijeet S.; Bhogala, Balakrishna R.; Maguire, Nuala M.; Maguire, Anita R.; Lawrence, Simon E. (American Chemical Society, 2018-07-03)

  Cocrystallization studies on Naringenin with 27 coformers have led to the formation of five new solid forms: a piperazinium salt (PIP+-NR-) and four cocrystals with the coformers flavone (FLV), 4-hydroxypyridine (4-HP), ...
• Direct arylation of 2-pyrones, coumarins, 2-pyridinones and 2-quinolones 

  Nolan, Marie-Therese (University College Cork, 2018)

  Direct arylation via C-H activation displays a number of advantages over traditional (Suzuki-Miyaura, Stille, etc.) coupling reactions. The 2-pyrone, coumarin, 2-pyridinone and 2-quinolone moieties are prevalent in numerous ...
• RNA G-quadruplexes and polyamines effects on translation: data analysis and development of software for ribosome pause prediction 

  Kumari, Romika (University College Cork, 2018)

  Ribosome profiling (Ribo-seq) technique provides a global snapshot of actively translating ribosomes by capturing the ribosome protected mRNA fragments. Ribo-seq technique can be implemented to study various translation ...
• Broadband Acoustic Resonance Dissolution Spectroscopy (BARDS): a novel approach to investigate the wettability of pharmaceutical powder blends 

  Peddapatla, Raghhu V. G.; Ahmed, M. Rizwan; Blackshields, Caroline A.; Sousa-Gallagher, Maria J.; McSweeney, Sean; Kruse, Jacob; Crean, Abina M.; Fitzpatrick, Dara (American Chemical Society, 2017-09-19)

  The ability of Broadband Acoustic Resonance Dissolution Spectroscopy (BARDS) to assess the wettability of powder blends is investigated. BARDS is a novel analytical technology developed based on the change in acoustic ...

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