Ellipticine and its derivatives are molecules which possess potent anticancer activity. This thesis explores the synthesis of novel ellipticine derivatives, as well as modifications of the template, and evaluates their ...

Broadband Acoustic Resonance Dissolution Spectroscopy (BARDS) is a novel analytical tool for the characterisation of powders, blends, tablets and a myriad of formulations. It is based on a phenomenon which occurs during ...

Chapter One of this thesis presents a consolidated review of methods for the formation of phosphorus-sulfur bonds. This review focuses on the synthesis of phosphorothioates, phosphonothioates, phosphinothioates and ...

Translation initiation is a complex process. The efficiency of translation initiation is determined not just by activity and availability of the translation initiation apparatus, but also the properties of mRNA 5’transcript ...

The first chapter provides an overview of the use of biocatalysis for the synthesis of pharmaceutical intermediates and natural products. This review focuses, in particular, on the impact of recent developments in technologies ...