This thesis describes the design and synthesis of novel rhodium carboxylates for use as enantioselective catalysts in transformations of α-diazocarbonyl compounds. Enantioselectivities of up to 93% ee were achieved in a ...

An ideal crystallisation process is predictable and reproducible; a less than simple ask. The influence of pre-nucleation molecular interactions in solution on the crystallised phase obtained has been highlighted. To improve ...

Tissue engineering is a multi-disciplinary field that involves three-dimensional cell and tissue models, live cell microscopy and related imaging modalities, along with fluorescence and phosphorescence-based biosensors. ...

Ellipticine and its derivatives are molecules which possess potent anticancer activity. This thesis explores the synthesis of novel ellipticine derivatives, as well as modifications of the template, and evaluates their ...

Broadband Acoustic Resonance Dissolution Spectroscopy (BARDS) is a novel analytical tool for the characterisation of powders, blends, tablets and a myriad of formulations. It is based on a phenomenon which occurs during ...