Development of stabilized vaccines with needle-free devices for targeted skin immunization

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dc.contributor.author Moore, Anne C.
dc.contributor.author Crean, Abina M.
dc.contributor.author O'Mahony, Conor
dc.contributor.editor Difford, Helen
dc.date.accessioned 2011-05-17T10:21:30Z
dc.date.available 2011-05-17T10:21:30Z
dc.date.issued 2010-12
dc.identifier.citation MOORE, A. C., CREAN, A. M. & O'MAHONY, C. 2010. Development of stabilized vaccines with needle-free devices for targeted skin immunization. European Pharmaceutical Review, 15(6), pp. 56-60. en
dc.identifier.volume 15 en
dc.identifier.issued 6 en
dc.identifier.startpage 56 en
dc.identifier.endpage 60 en
dc.identifier.issn 1759-1279
dc.identifier.uri http://hdl.handle.net/10468/306
dc.description.abstract Vaccination represents the primary public health measure to combat infectious diseases. However, limitations of cold-chain storage, vaccine wastage, hazardous sharps-waste and the requirements for trained personnel add significant and unsustainable financial and logistic costs to immunisation programmes. Developments of needle-free methods should aim to overcome these logistics issues from the very start of the vaccine production process. Dermal vaccine administration using microneedle-based devices promises to be one such needle-free method that addresses all of these issues. Methods of stabilisation of vaccines onto or incorporated into microneedles should be developed to permit seamless transition and cost-effectiveness from vaccine bulk-up to final product. This review examines recent developments in microneedle technology and highlights the current challenges to translate this technology into practice. en
dc.format.mimetype application/pdf en
dc.language.iso en en
dc.publisher Russell Publishing Limited en
dc.relation.uri http://www.europeanpharmaceuticalreview.com/
dc.rights ©European Pharmaceutical Review en
dc.subject Vaccine delivery en
dc.subject Microneedle en
dc.subject.lcsh Immunization en
dc.title Development of stabilized vaccines with needle-free devices for targeted skin immunization en
dc.type Article (non peer-reviewed) en
dc.internal.authorurl http://publish.ucc.ie/researchprofiles/C019/annemoore en
dc.internal.authorurl http://publish.ucc.ie/researchprofiles/C019/acrean en
dc.internal.authorcontactother Anne Moore, Pharmacology & Therapeutics, University College Cork, Cork, Ireland. +353-21-490-3000 Email: anne.moore@ucc.ie en
dc.internal.authorcontactother Abina Cream, Pharmacy, University College Cork, Cork, Ireland. +353-21-490-3000 Email: a.crean@ucc.ie en
dc.internal.authorcontactother Conor O'Mahony, Tyndall National Institute, Lee Maltings, Cork, Ireland. Email: conor.omahony@tyndall.ie en
dc.internal.availability Full text available en
dc.internal.webversions http://www.europeanpharmaceuticalreview.com
dc.date.updated 2011-04-20T13:57:15Z
dc.description.version Accepted Version en
dc.internal.rssid 69323984
dc.description.status Not peer reviewed en
dc.identifier.journaltitle European Pharmaceutical Review en
dc.internal.copyrightchecked E-mail from editor, Helen Difford 28 Mar 2011. "I can confirm that Anne’s article can be included in the institutional repository. I think you’ve already covered our conditions, we just request that no amends be made to the article from as it was when published and that European Pharmaceutical Review is given full copyright." en
dc.internal.IRISemailaddress anne.moore@ucc.ie en
dc.internal.IRISemailaddress conor.omahony@tyndall.ie en


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