Development of an intervention to support medication management in patients with multimorbidity in primary care

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dc.contributor.advisor Bradley, Colin P. en
dc.contributor.author Sinnott, Carol
dc.date.accessioned 2017-01-11T13:22:15Z
dc.date.issued 2016
dc.date.submitted 2016
dc.identifier.citation Sinnott, C. 2016. Development of an intervention to support medication management in patients with multimorbidity in primary care. PhD Thesis, University College Cork. en
dc.identifier.endpage 344 en
dc.identifier.uri http://hdl.handle.net/10468/3465
dc.description.abstract The overarching aim of this thesis was to develop an intervention to support patient-centred prescribing in the context of multimorbidity in primary care. Methods A range of research methods were used to address different components of the Medical Research Council, UK (MRC) guidance on the development and evaluation of complex interventions in health care. The existing evidence on GPs’ perceptions of the management of multimorbidity was systematically reviewed. In qualitative interviews, chart-stimulated recall was used to explore the challenges experienced by GPs when prescribing for multimorbid patients. In a cross-sectional study, the psychosocial issues that complicate the management of multimorbidity were examined. To develop the complex intervention, the Behaviour Change Wheel (BCW) was used to integrate behavioural theory with the findings of these three studies. A feasibility study of the new intervention was then conducted with GPs. Results The systematic review revealed four domains of clinical practice where GPs experienced difficulties in multimorbidity. The qualitative interview study showed that GPs responded to these difficulties by ‘satisficing’. In multimorbid patients perceived as stable, GPs preferred to ‘maintain the status quo’ rather than actively change medications. In the cross-sectional study, the significant association between multimorbidity and negative psychosocial factors was shown. These findings informed the development of the ‘Multimorbidity Collaborative Medication Review and Decision-making’ (MY COMRADE) intervention. The intervention involves peer support: two GPs review the medications prescribed to a complex multimorbid patient together. In the feasibility study, GPs reported that the intervention was appropriate for the context of general practice; was widely applicable to their patients with multimorbidity; and recommendations for optimising medications arose from all collaborative reviews. Conclusion Applying theory to empirical data has led to an intervention that is implementable in clinical practice, and has the potential to positively change GPs’ behaviour in the management of medications for patients with multimorbidity. en
dc.description.sponsorship Health Research Board (Grant HRB/NSAFP/2011/3) en
dc.format.mimetype application/pdf en
dc.language English en
dc.language.iso en en
dc.publisher University College Cork en
dc.rights © 2016, Carol Sinnott. en
dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/3.0/ en
dc.subject Multimorbidity en
dc.subject General practice en
dc.subject Qualitative research en
dc.subject Medication management en
dc.subject Intervention development en
dc.title Development of an intervention to support medication management in patients with multimorbidity in primary care en
dc.type Doctoral thesis en
dc.type.qualificationlevel Doctoral en
dc.type.qualificationname PhD (Medicine and Health) en
dc.internal.availability Full text not available en
dc.check.info Indefinite en
dc.check.date 10000-01-01
dc.description.version Accepted Version
dc.contributor.funder Health Research Board en
dc.description.status Not peer reviewed en
dc.internal.school General Practice en
dc.check.reason This thesis is due for publication or the author is actively seeking to publish this material en
dc.check.opt-out Not applicable en
dc.thesis.opt-out false
dc.check.chapterOfThesis Chapters 7, 10
dc.check.embargoformat E-thesis on CORA only en
ucc.workflow.supervisor c.bradley@ucc.ie
dc.internal.conferring Autumn 2016 en


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