Herpetic tracheitis in association with rituximab therapy

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dc.contributor.author Thong, Lorraine
dc.contributor.author Plant, Barry J.
dc.contributor.author McCarthy, Julie
dc.contributor.author Murphy, Desmond M.
dc.date.accessioned 2017-01-23T10:21:02Z
dc.date.available 2017-01-23T10:21:02Z
dc.date.issued 2016-05-05
dc.identifier.citation Thong, L., Plant, B. J., McCarthy, J. and Murphy, D. M. (2016) 'Herpetic tracheitis in association with rituximab therapy', Respirology Case Reports, 4(4), e00158. doi:10.1002/rcr2.158 en
dc.identifier.volume 4 en
dc.identifier.issued 4 en
dc.identifier.startpage e00158-1 en
dc.identifier.endpage e00158-3 en
dc.identifier.issn 2051-3380
dc.identifier.uri http://hdl.handle.net/10468/3497
dc.identifier.doi 10.1002/rcr2.158
dc.description.abstract A 58-year old lady under active follow-up with the respiratory services at our institution for bronchiectasis secondary to hypogammaglobulinaemia presented with hoarseness and haemoptysis. She was also receiving rituximab maintenance therapy for follicular lymphoma. Bronchoscopy demonstrated vesicular lesions on her vocal cords and trachea, confirmed as herpes simplex virus (HSV) on cytological analysis of brushings. She responded well to intravenous valacyclovir. Rituximab is increasingly utilised in the treatment of haematological and auto-immune disorders. This case highlights the potential of this drug to potentiate susceptibility to infection in an already immunocompromised individual. en
dc.format.mimetype application/pdf en
dc.language.iso en en
dc.publisher Wiley en
dc.rights © 2016 The Authors. Respirology Case Reports published by John Wiley & Sons Australia, Ltd on behalf of The Asian Pacific Society of Respirology. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made. en
dc.rights.uri https://creativecommons.org/licenses/by-nc/4.0/ en
dc.subject Herpes simplex en
dc.subject Immunosuppression en
dc.subject Non-Hodgkin's lymphoma en
dc.subject Rituximab en
dc.subject Tracheitis en
dc.title Herpetic tracheitis in association with rituximab therapy en
dc.type Article (peer-reviewed) en
dc.internal.authorcontactother Desmond Murphy, Medicine, University College Cork, Cork, Ireland. +353-21-490-3000 Email: des.murphy@ucc.ie en
dc.internal.availability Full text available en
dc.date.updated 2017-01-23T10:12:25Z
dc.description.version Published Version en
dc.internal.rssid 380746083
dc.description.status Peer reviewed en
dc.identifier.journaltitle Respirology Case Reports en
dc.internal.copyrightchecked No !!CORA!! en
dc.internal.licenseacceptance Yes en
dc.internal.IRISemailaddress des.murphy@ucc.ie en
dc.internal.IRISemailaddress b.plant@ucc.ie en


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© 2016 The Authors. Respirology Case Reports published by John Wiley & Sons Australia, Ltd on behalf of The Asian Pacific Society of Respirology. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made. Except where otherwise noted, this item's license is described as © 2016 The Authors. Respirology Case Reports published by John Wiley & Sons Australia, Ltd on behalf of The Asian Pacific Society of Respirology. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
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