• Somatostatin receptors as a new active targeting sites for nanoparticles 

  Abdellatif, Ahmed A. H.; Aldalaen, Sa'ed M.; Faisal, Waleed; Tawfeek, Hesham M. (Elsevier B.V., 2018)

  The delivery of nanoparticles through receptor-mediated cell interactions has nowadays a major attention in the area of drug targeting applications. This specific kind of targeting is mediated by localized receptors impeded ...
• Development of a novel single-use microneedle design platform for increased patient compliance 

  Márquez-Graña, C.; Bryan, K.; Vucen, Sonja; O'Sullivan, Caroline (Elsevier B.V., 2017)

  Microneedles (MN) skin patches are novel medical devices in micron scale with a needle array which offers an alternative drug delivery system to conventional methods. MN patches are applied onto the skin reaching the dermal ...
• Mechanistic understanding of bioenabling formulation approaches to improve oral bioavailability using porcine in vivo and in silico models 

  O'Shea, Joseph P. (University College Cork, 2018)

  Objectives: Mesoporous silicas (SLC) have demonstrated considerable potential to improve bioavailability of poorly soluble drugs by facilitating rapid dissolution and generating supersaturation. The addition of certain ...
• Biosimilar infliximab introduction into the gastro-enterology care pathway in a large acute Irish teaching hospital: a story behind the evidence 

  O'Brien, Gary L.; Carrol, Donal; Mulcahy, Mark; Walshe, Valerie; Courtney, Garry; Byrne, Stephen (Pro Pharma Communications International, 2018-02-27)

  Background and aim: Biosimilar medicines are not considered exact replicas of originator biological medicines. As a result, prescribers can be hesitant to introduce such medicines into the clinical setting until evidence ...
• Cost-effectiveness analysis of a physician-implemented medication screening tool in older hospitalised patients in Ireland 

  O'Brien, Gary L.; O'Mahony, Denis; Gillespie, Paddy; Mulcahy, Mark; Walshe, Valerie; O'Connor, Marie N.; O'Sullivan, David; Gallagher, James; Byrne, Stephen (Springer International Publishing AG, 2018-07-13)

  Background: A recent randomised controlled trial conducted in an Irish University teaching hospital that evaluated a physician-implemented medication screening tool, demonstrated positive outcomes in terms of a reduction ...

View more