Introduction: Developed in the late 20th century, the conceptual descriptive framework for this thesis was inspired by Walt and Gilson’s health policy triangle (HPT). The HPT model is a policy analysis framework universally ...
Dennehy, Olga C.(University College Cork, 2020-04)
α-Thio-β-chloroacrylamides are a class of highly versatile synthetic intermediates due to their diverse functionality. The three step synthesis to form these compounds provided a model system to optimise and scale-up a ...
Antibodies form the main class of commercial therapeutic proteins and are intended for the treatment of several chronic diseases. The current trend is to formulate antibodies at high concentrations in order to deliver a ...
Keane, Jonathan M.; Joyce, Susan A.; Gahan, Cormac G. M.; Hyland, Niall P.; Houston, Aileen(Springer Nature Switzerland AG, 2020-12-03)
The symbiosis between the gut microbiota and the host has been identified as an integral part of normal human physiology and physiological development. Research in germ-free or gnotobiotic animals has demonstrated the ...
Lyons, Thérèse; Gahan, Cormac G. M.; O'Sullivan, Timothy P.(Newlands Press, 2020-10-23)
Since their initial isolation from the marine alga Delisea pulchra, bromofuranones have been investigated as potential inhibitors of quorum sensing (QS) in various bacterial strains. QS is an important mechanism by which ...
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