• Impact of host and environmental factors on β-glucuronidase enzymatic activity: implications for gastrointestinal serotonin 

  Walsh, Jacinta; Olavarria-Ramirez, Loreto; Lach, Gilliard; Boehme, Marcus; Dinan, Timothy G.; Cryan, John F.; Griffin, Brendan T.; Hyland, Niall P.; Clarke, Gerard (American Physiological Society, 2020-03-09)

  The gastrointestinal tract houses a reservoir of bacterial-derived enzymes which can directly catalyze the metabolism of drugs, dietary elements, and endogenous molecules. Both host and environmental factors may influence ...
• Out of pocket or out of control: A qualitative analysis of healthcare professional stakeholder involvement in pharmaceutical policy change in Ireland 

  O'Brien, Gary L.; Sinnott, Sarah-Jo; O'Flynn, Bridget; Walshe, Valerie; Mulcahy, Mark; Byrne, Stephen (Elsevier B.V., 2020-02-28)

  Background: Mandatory co-payments attached to prescription medicines on the Irish public health insurance [General Medical Services (GMS)] scheme have undergone multiple iterations since their introduction in October 2010. ...
• A study of magnesium stearate behaviour in pharmaceutical blends and tablets employing Broadband Acoustic Resonance Dissolution Spectroscopy (BARDS) 

  Peddapatla, Raghu V. G. (University College Cork, 2019)

  Magnesium Stearate (MgSt) is the most commonly used lubricant in pharmaceutical industries. Effects of MgSt on the final product have been extensively studied in batch processing. In recent times pharmaceutical companies ...
• Perceived stress experienced by undergraduate healthcare professional students throughout their degree 

  Casey, Rachel; O'Doherty, Julia; Murphy, Kevin D.; Sahm, Laura J. (2020-02-13)

  Rationale: Stress can be a part of third level education and experienced by undergraduate students across a range of degree courses. Stress can be positive in stimulating optimum performance. However, excessive stress ...
• Application of a physiologically-based pharmacokinetic model for the prediction of bumetanide plasma and brain concentrations in the neonate 

  Donovan, Maria D.; Abduljalil, Khaled; Cryan, John F.; Boylan, Geraldine B.; Griffin, Brendan T. (Wiley, 2018-01-10)

  Bumetanide is a loop diuretic that is proposed to possess a beneficial effect on disorders of the central nervous system, including neonatal seizures. Therefore, prediction of unbound bumetanide concentrations in the brain ...

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