The changing phenotype of Inflammatory Bowel Disease

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Date
2016-11
Authors
Moran, Carthage
Sheehan, Donal
Shanahan, Fergus
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Hindawi Publishing Corporation
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Abstract
It is widely known that there have been improvements in patient care and an increased incidence of Inflammatory Bowel Disease (IBD) worldwide in recent decades. However, less well known are the phenotypic changes that have occurred; these are discussed in this review. Namely, we discuss the emergence of obesity in patients with IBD, elderly onset disease, mortality rates, colorectal cancer risk, the burden of medications and comorbidities, and the improvement in surgical treatment with a decrease in surgical rates in recent decades.
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Keywords
Body-mass index , Population-based cohort , Primary sclerosing cholangitis , Cause-specific mortality , Pouch-anal anastomosis , Ulcerative colitis data , Crohn's disease
Citation
Moran, C., Sheehan, D. and Shanahan, F. (2016) 'The changing phenotype of Inflammatory Bowel Disease', Gastroenterology Research and Practice, 1619053 (9pp). doi: 10.1155/2016/1619053