• MicroRNA expression and function in neonatal hypoxic ischaemic encephalopathy 

  Looney, Ann-Marie (University College Cork, 2016)

  Hypoxic ischaemic encephalopathy (HIE) is a devastating neonatal condition which affects 2-3 per 1000 infants annually. The current gold standard of treatment - induced hypothermia, has the ability to reduce neonatal ...
• Hepatitis C virus modulation of lipid and autophagy pathways 

  Harty, Ciara (University College Cork, 2016)

  Hepatitis C virus [HCV] infects 170 million people worldwide. We investigated interactions between HCV proteins and cellular proteins involved in autophagy and lipid metabolism. We sought to develop an infection model using ...
• Investigating metabolomic biomarkers of hypoxic ischaemic encephalopathy 

  Denihan, Niamh Marie (University College Cork, 2016)

  Background An early objective biomarker to predict the severity of hypoxic-ischaemic encephalopathy (HIE) and identify infants suitable for intervention remains elusive. This thesis aims to progress metabolomic markers of ...
• Development of a novel probe integrated with a micro-structured impedance sensor for the detection of breast cancer 

  Savage, Niall Thomas Patrick (University College Cork, 2016)

  The work described in this thesis focuses on the development of an innovative bioimpedance device for the detection of breast cancer using electrical impedance as the detection method. The ability for clinicians to detect ...
• Development of a dissolvable microneedle influenza vaccine patch 

  Allen, Evin (University College Cork, 2016)

  Delivery of large molecular weight biological molecules to the epidermis and dermis is constrained by the tough outer layer of the epidermis, the stratum corneum (sc). Microneedle technologies attempt to overcome this ...

View more