• Acetylated microtubules are essential for touch sensation in mice 

  Morley, Shane J. (University College Cork, 2016)

  The sense of touch depends upon the transformation of mechanical energy into electrical signals by peripheral sensory neurons and associated cells in the skin. This conversion is thought to be mediated by a complex of ...
• Short interval change in hepatitis C hypervariable region 1 in chronic infection. Are there treatment windows in the envelope? 

  Schmidt-Martin, Daniel (University College Cork, 2016)

  Hepatitis C Virus (HCV), an RNA virus, is one of the leading causes of cirrhosis worldwide and, remains the leading indication for orthoptic liver transplantation in the United States. Dual treatment with pegylated interferon ...
• Evaluation of the role of autophagy in acute myeloid leukaemic cell differentiation 

  Orfali, Nina (University College Cork, 2017)

  Acute myeloid leukemia (AML) is a malignancy characterized by the accumulation of white blood cell precursors in the bone marrow and circulation. Treatment regimens for this disease are notoriously toxic and survival is ...
• Novel strategies to enhance bumetanide concentrations in the brain in the treatment of neonatal seizures 

  Donovan, Maria D. (University College Cork, 2015)

  Seizures are a prevalent neurodevelopmental disorder that affect up to 5/1000 newborns. Seizures result in detrimental developmental outcomes for many neonates, including mortality, disability and epilepsy. Current ...
• In vitro infectivity of the Hepatitis C Virus in the context of humoral immunity and immune escape 

  Naik, Amruta S. (University College Cork, 2017)

  The hepatitis C virus (HCV) is an enveloped virus which circulates in infected individuals as a quasispecies. HCV encodes two highly glycosylated envelope glycoproteins E1E2 which is involved in fusion and entry of the ...

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