• Investigations into the role of microbiota-gut-brain axis on behaviour and physiology in the mouse 

  O'Connor, Rory (University College Cork, 2019-12-16)

  The growing recognition of the influence of the intestinal microbiota over the brain and behaviour has led to a shift in the world of neuroscience. Recent developments in the understanding of the microbiota-gut-brain axis ...
• Novel insights into the mechanisms underlying the anti-obesity effects of whey protein 

  Boscaini, Serena (University College Cork, 2020-09-25)

  Obesity has become one of the major health problems worldwide, due to modern eating habits and an increase in sedentary lifestyles. Dietary strategies represent one among different therapeutic approaches employed to ...
• Using the health policy triangle framework to describe local, regional and national healthcare policy changes within Ireland's diverse healthcare settings 

  O'Brien, Gary L. (University College Cork, 2020)

  Introduction: Developed in the late 20th century, the conceptual descriptive framework for this thesis was inspired by Walt and Gilson’s health policy triangle (HPT). The HPT model is a policy analysis framework universally ...
• Optimisation of gene editing for cystic fibrosis 

  Mention, Karen (University College Cork, 2020-06-06)

  Cystic Fibrosis (CF) is a recessive genetic disease caused by mutations in the Cystic Fibrosis Transmembrane conductance Regulator (CFTR) gene. To date, 352 variants in the CFTR gene have been shown to be CF-causing. CF ...
• Scale-up and optimisation of the β-chloroacrylamide process by batch and continuous flow methods 

  Dennehy, Olga C. (University College Cork, 2020-04)

  α-Thio-β-chloroacrylamides are a class of highly versatile synthetic intermediates due to their diverse functionality. The three step synthesis to form these compounds provided a model system to optimise and scale-up a ...

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