• Pharmacological optimisation of ultrasound guided axillary brachial plexus block 

  Malladihalli Ranganath, Anil Kumar (University College Cork, 2021-07)

  Regional anaesthesia provide significant advantages in the perioperative care of the patient undergoing surgery, including improved postoperative analgesia, a reduction in adverse events, shorter recovery time, and expedited ...
• A mixed methods study of the relationship between organisational readiness to change, service user engagement and innovation adoption in community-based opiate substitute treatment services in Ireland 

  Kelly, Peter (University College Cork, 2021-06)

  Introduction: While we know that treatment for opiate dependence, such as opiate substitution therapy and psychosocial interventions delivered in community settings are effective, we do not know exactly why they are ...
• Defining the potential of class-IIa histone deacetylases as a therapeutic target for Parkinson’s disease 

  Mazzocchi, Martina (University College Cork, 2021-11-15)

  Parkinson’s disease (PD) is a neurodegenerative disease characterized by early dopaminergic (DA) neuron degeneration, coupled with intracellular aggregation of α-synuclein (α-syn) in Lewy Bodies (LB). Given the lack of a ...
• Surguvant inflammation and metabolism in colorectal surgery 

  Fleming, Christina A. (University College Cork, 2020)

  Background: It is believed that dysregulated perioperative inflammation (POI) and altered cellular and systemic metabolism in the perioperative period may predispose to colon cancer recurrence. This thesis examined the ...
• Synthesis and evaluation of novel quorum sensing inhibitors 

  Lyons, Thérèse (University College Cork, 2021-07-01)

  This thesis details the synthesis of a range of furanones and the subsequent evaluation of their quorum sensing inhibitory effects. Chapter One focuses on the role of quorum sensing in bacteria and fungi. It explores the ...

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