• An exploration of deprescribing barriers and facilitators for older patients in primary care in Ireland – the potential role of the pharmacist 

  Hansen, Christina Raae (University College Cork, 2019)

  Introduction: The older population, often defined as people aged ≥ 65 years is growing. With older age, the risk of multimorbidity (commonly defined as the presence of ≥ 2 chronic conditions) increases together with the ...
• The characterization of macrophages in melanoma and the effect of electroporation on melanoma conditioned macrophages 

  Tremble, Liam Friel (University College Cork, 2019)

  Approximately 11,000 people are diagnosed with skin cancer in Ireland every year and approximately 1,000 of these present with malignant melanoma. Due to lifestyle changes and an increase in UV exposure, incidences are ...
• Investigating the mechanisms by which PINK1 protects against Parkinson's disease 

  Furlong, Rachel (University College Cork, 2019)

  PINK1 (PTEN-induced putative kinase-1) functions as a ubiquitous serine-threonine kinase, with pro-survival, neuroprotective and anti-stress signalling functions. Autosomal recessive mutations in PINK1, resulting in a loss ...
• Gut microbiota-mediated bile acid metabolism: implications for oral drug absorption 

  Enright, Elaine F. (University College Cork, 2019)

  In recent years, it has been elucidated that, in addition to host genetics, the gut microbiome must be considered as a source of pharmacokinetic variability. As newly emerging drug candidates trend toward low solubility ...
• Understanding mental health nurses' lived experience of self-care at work: an interpretative phenomenological analysis 

  O'Malley, Maria (University College Cork, 2019)

  Background: Nurses experience stress and distress at work, impacting at organisational, practice and personal levels. Self-care can support and value the integral role of nurses in quality healthcare delivery. Self-care ...

View more