Worldwide prevalence of tocophobia in pregnant women: systematic review and meta-analysis

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dc.contributor.author O'Connell, Maeve A.
dc.contributor.author Leahy-Warren, Patricia
dc.contributor.author Khashan, Ali S.
dc.contributor.author Kenny, Louise C.
dc.contributor.author O'Neill, Sinéad M.
dc.date.accessioned 2017-06-02T14:34:04Z
dc.date.available 2017-06-02T14:34:04Z
dc.date.issued 2017-03-30
dc.identifier.citation O'Connell, M. A., Leahy-Warren, P., Khashan, A. S., Kenny, L. C. and O'Neill, S. M. 'Worldwide prevalence of tocophobia in pregnant women: systematic review and meta-analysis', Acta Obstetricia et Gynecologica Scandinavica, doi:10.1111/aogs.13138 In Press en
dc.identifier.issn 1600-0412
dc.identifier.uri http://hdl.handle.net/10468/4050
dc.identifier.doi 10.1111/aogs.13138
dc.description.abstract Introduction: Tocophobia is defined as a severe fear of pregnancy and childbirth. There is increasing evidence that tocophobia may have short-term and long-term adverse effects on mother and baby. We performed a systematic review and meta-analysis to determine the global prevalence of tocophobia in pregnancy. Material and methods: Relevant articles were identified through searching six relevant databases: MEDLINE, CINAHL, Pubmed, PsycINFO, Maternity & Infant Care and Scopus between 1946 and April 2016. We used search terms for tocophobia prevalence in pregnant women that we agreed with a medical librarian. There were no language restrictions. Two review authors independently assessed data for inclusion, extracted data and assessed quality using a standardized appraisal tool. Meta-analysis was performed to determine the overall pooled-prevalence of tocophobia. Several subgroup and sensitivity analyses were conducted. Results: Thirty-three studies were included in the systematic review from 18 countries of which data from 29 studies were used in the meta-analysis of 853 988 pregnant women. Definition of tocophobia varied, whereas prevalence rates ranged between 3.7 and 43%. The overall pooled prevalence of tocophobia, using a random-effects model, was 14% (95% CI 0.12â 0.16). Significant heterogeneity was observed (I2 = 99.25%, p = 0.00), which was not explained in subgroup analyses including tocophobia definition used, screening trimester and parity. Conclusion: The prevalence of tocophobia is estimated at 14% and appears to have increased in recent years (2000 onwards). Considerable heterogeneity (99.25%) was noted that may be attributed to lack of consensus on the definition of tocophobia, so our results should be interpreted with caution. en
dc.description.sponsorship Science Foundation Ireland (SFI grant number 12/RC/2272) en
dc.format.mimetype application/pdf en
dc.language.iso en en
dc.publisher Wiley en
dc.rights © 2017 Nordic Federation of Societies of Obstetrics and Gynecology. This is the peer reviewed version of the following article: Worldwide prevalence of tocophobia in pregnant women: systematic review and meta-analysis. Acta Obstet Gynecol Scand 2017, which has been published in final form at http://dx.doi.org/10.1111/aogs.13138. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving. en
dc.subject Epidemiology en
dc.subject Fear of childbirth en
dc.subject Pregnancy en
dc.subject Systematic review en
dc.subject Tocophobia en
dc.subject W-DEQ A en
dc.title Worldwide prevalence of tocophobia in pregnant women: systematic review and meta-analysis en
dc.type Article (peer-reviewed) en
dc.internal.authorcontactother Maeve O'Connell, Obstetrics & Gynaecology, University College Cork, Cork, Ireland. +353-21-490-3000 Email: maeveoconnell@ucc.ie en
dc.internal.availability Full text available en
dc.check.info Access to this article is restricted until 12 months after publication at the request of the publisher en
dc.check.date 2018-03-30
dc.date.updated 2017-06-02T14:26:16Z
dc.description.version Accepted Version en
dc.internal.rssid 397415135
dc.contributor.funder Science Foundation Ireland en
dc.description.status Peer reviewed en
dc.identifier.journaltitle Acta Obstetricia Et Gynecologica Scandinavica en
dc.internal.copyrightchecked No !!CORA!! en
dc.internal.licenseacceptance Yes en
dc.internal.IRISemailaddress maeveoconnell@ucc.ie en


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