The contribution of microbial biotechnology to sustainable development goals: microbiome therapies

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dc.contributor.author O'Toole, Paul W.
dc.contributor.author Paoli, Max
dc.date.accessioned 2017-10-18T09:40:12Z
dc.date.available 2017-10-18T09:40:12Z
dc.date.issued 2017
dc.identifier.citation O'Toole, P. W. and Paoli, M. (2017) 'The contribution of microbial biotechnology to sustainable development goals: microbiome therapies', Microbial Biotechnology, 10(5), pp. 1066-1069. doi: 10.1111/1751-7915.12752 en
dc.identifier.volume 10
dc.identifier.issued 5
dc.identifier.startpage 1066
dc.identifier.endpage 1069
dc.identifier.issn 1751-7915
dc.identifier.uri http://hdl.handle.net/10468/4881
dc.identifier.doi 10.1111/1751-7915.12752
dc.description.abstract Complex communities of microbes live on and in plants, humans and other animals. These communities are collectively referred to as the microbiota or microbiome. Plants and animals evolved to co-exist with these microbes. In mammals, particular kinds of alteration of the microbiome (dysbiosis) are associated with loss of health, most likely due to loss of microbial metabolites, signalling molecules, or regulators of host pathways. Modern life-style diseases such as Inflammatory Bowel Disease (IBD), Irritable Bowel Syndrome (IBS), type 2 diabetes, obesity and metabolic syndrome have been linked to dysbiosis. These multifactorial diseases involve multiple risk factors and triggers, depletion of certain gut microbiota species being one of them. Live Biotherapeutics operate by restoring microbial products or activities in affected subjects. They are being developed as adjuncts, alternatives or new treatment options for diseases that affect a growing proportion of global citizens. en
dc.description.sponsorship Science Foundation Ireland (APC Microbiome Institute); Department of Agriculture, Food and the Marine (FIRM (ELDERFOOD and IMMUNOMET) en
dc.format.mimetype application/pdf en
dc.language.iso en en
dc.publisher John Wiley & Sons, Inc. en
dc.relation.uri http://onlinelibrary.wiley.com/doi/10.1111/1751-7915.12752/abstract
dc.rights © 2017, the Authors. Microbial Biotechnology published by John Wiley & Sons Ltd and Society for Applied Microbiology. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. en
dc.rights.uri https://creativecommons.org/licenses/by/4.0/
dc.subject Microbiota en
dc.subject Diseases en
dc.subject Biotechnology en
dc.title The contribution of microbial biotechnology to sustainable development goals: microbiome therapies en
dc.type Article (peer-reviewed) en
dc.internal.authorcontactother Paul O'Toole, Microbiology, University College Cork, Cork, Ireland. +353-21-490-3000. Email: pwotoole@ucc.ie en
dc.internal.availability Full text available en
dc.description.version Published Version en
dc.contributor.funder Seventh Framework Programme
dc.contributor.funder Department of Agriculture, Food and the Marine
dc.contributor.funder Science Foundation Ireland
dc.description.status Peer reviewed en
dc.identifier.journaltitle Microbial Biotechnology en
dc.internal.IRISemailaddress pwotoole@ucc.ie en
dc.relation.project info:eu-repo/grantAgreement/EC/FP7::SP1::KBBE/613979/EU/Microbiome Influence on Energy balance and Brain Development-Function Put into Action to Tackle Diet-related Diseases and Behavior./MYNEWGUT
dc.relation.project info:eu-repo/grantAgreement/EC/FP7::SP1::KBBE/266486/EU/New dietary strategies addressing the specific needs of elderly population for an healthy ageing in Europe/NU-AGE


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© 2017, the Authors. Microbial Biotechnology published by John Wiley & Sons Ltd and Society for Applied Microbiology. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. Except where otherwise noted, this item's license is described as © 2017, the Authors. Microbial Biotechnology published by John Wiley & Sons Ltd and Society for Applied Microbiology. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
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