Toward a personalized real-time diagnosis in neonatal seizure detection
Temko, Andriy; Sarkar, Achintya K. R.; Boylan, Geraldine B.; Mathieson, Sean; Marnane, William P.; Lightbody, Gordon
Date:2017-09-11
Copyright:This work is licensed under a Creative Commons Attribution 3.0 License. For more information, see http://creativecommons.org/licenses/by/3.0/
Citation:Temko, A., Sarkar, A. K., Boylan, G. B., Mathieson, S., Marnane, W. P. and Lightbody, G. (2017) 'Toward a personalized real-time diagnosis in neonatal seizure detection', IEEE Journal of Translational Engineering in Health and Medicine, 5, 2800414 (14pp). doi: 10.1109/JTEHM.2017.2737992
The problem of creating a personalized seizure detection algorithm for newborns is tackled in this paper. A probabilistic framework for semi-supervised adaptation of a generic patient-independent neonatal seizure detector is proposed. A system that is based on a combination of patient-adaptive (generative) and patient-independent (discriminative) classifiers is designed and evaluated on a large database of unedited continuous multichannel neonatal EEG recordings of over 800 h in duration. It is shown that an improvement in the detection of neonatal seizures over the course of long EEG recordings is achievable with on-the-fly incorporation of patient-specific EEG characteristics. In the clinical setting, the employment of the developed system will maintain a seizure detection rate at 70% while halving the number of false detections per hour, from 0.4 to 0.2 FD/h. This is the first study to propose the use of online adaptation without clinical labels, to build a personalized diagnostic system for the detection of neonatal seizures.
Except where otherwise noted, this item's license is described as This work is licensed under a Creative Commons Attribution 3.0 License. For more information, see http://creativecommons.org/licenses/by/3.0/
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