Introduction: Despite the well-documented association between potentially inappropriate prescribing (PIP) and adverse outcomes for hospitalised older adults, the prevalence of PIP remains unacceptably high. Recommendations ...

Introduction: The older population, often defined as people aged ≥ 65 years is growing. With older age, the risk of multimorbidity (commonly defined as the presence of ≥ 2 chronic conditions) increases together with the ...

In recent years, it has been elucidated that, in addition to host genetics, the gut microbiome must be considered as a source of pharmacokinetic variability. As newly emerging drug candidates trend toward low solubility ...

Mesoporous silica materials have been investigated as novel formulation aids for oral drug delivery due to their drug solubility enhancing characteristics. However, the mechanism of drug release from these systems is not ...

The regulation of food intake is one of the most intricate internal balances in mammalian behaviour. Dysregulation of the central mechanisms underlying appetite control and metabolism result in both disorders of under- and ...