Low-dose carotid computed tomography angiography using pure iterative reconstruction

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dc.contributor.author Moloney, Fiachra
dc.contributor.author Murphy, Kevin P.
dc.contributor.author Twomey, Maria
dc.contributor.author Crish, Lee
dc.contributor.author Canniffe, Emma M.
dc.contributor.author McLaughlin, Patrick D.
dc.contributor.author Moore, Niamh
dc.contributor.author O'Keefe, Michael
dc.contributor.author O'Neill, Siobhán B.
dc.contributor.author Manning, Brian M.
dc.contributor.author Wyse, Gerald
dc.contributor.author Fanning, Noel
dc.contributor.author O'Connor, Owen J.
dc.contributor.author Maher, Michael M.
dc.date.accessioned 2018-08-16T13:30:22Z
dc.date.available 2018-08-16T13:30:22Z
dc.date.issued 2016-09
dc.identifier.citation Moloney, F., Murphy, K. P., Twomey, M., Crush, L., Canniffe, E. M., McLaughlin, P. D., Moore, N., O'Keeffe, M., O'Neill, S., Manning, B. M., Wyse, G., Fanning, N., O'Connor, O. J. and Maher, M. M. (2016) 'Low-Dose Carotid Computed Tomography Angiography Using Pure Iterative Reconstruction', Journal of Computer Assisted Tomography, 40(5), pp. 833-839. doi: 10.1097/RCT.0000000000000436 en
dc.identifier.volume 40 en
dc.identifier.issued 5 en
dc.identifier.startpage 833 en
dc.identifier.endpage 839 en
dc.identifier.issn 0363-8715
dc.identifier.uri http://hdl.handle.net/10468/6618
dc.identifier.doi 10.1097/RCT.0000000000000436
dc.description.abstract The aim of this study was to assess if a low-dose carotid computed tomography angiography (CTA) performed with pure iterative reconstruction (IR) is comparable to a conventional dose CTA protocol. Methods: Twenty patients were included. Radiation dose was divided into a low-dose acquisition reconstructed with pure IR and a conventional dose acquisition reconstructed with 40% hybrid IR. Dose, image noise, contrast resolution, spatial resolution, and carotid artery stenosis were measured. Results: Mean effective dose was significantly lower for low-dose than conventional dose studies (1.84 versus 3.71 mSv; P < 0.001). Subjective image noise, contrast resolution, and spatial resolution were significantly higher for the low-dose studies. There was excellent agreement for stenosis grading accuracy between low- and conventional dose studies (Cohen κ = 0.806). Conclusions: A low-dose carotid CTA protocol reconstructed with pure IR is comparable to a conventional dose CTA protocol in terms of image quality and diagnostic accuracy while enabling a dose reduction of 49.6%. en
dc.format.mimetype application/pdf en
dc.language.iso en en
dc.publisher Lippincott, Williams & Wilkins en
dc.relation.uri https://journals.lww.com/jcat/Fulltext/2016/09000/Low_Dose_Carotid_Computed_Tomography_Angiography.26.aspx
dc.rights © 2016 Wolters Kluwer Health, Inc. All rights reserved. en
dc.subject CT angiography en
dc.subject MBIR en
dc.subject pure iterative reconstruction en
dc.subject Angiography en
dc.subject Carotid artery disease en
dc.subject Multidetector CT en
dc.subject Radiation dose en
dc.subject Stroke en
dc.subject Pure iterative reconstruction en
dc.title Low-dose carotid computed tomography angiography using pure iterative reconstruction en
dc.type Article (peer-reviewed) en
dc.internal.authorcontactother Owen O'Connor, Medicine , University College Cork, Cork, Ireland. +353-21-490-3000 Email: oj.oconnor@ucc.ie en
dc.internal.availability Full text available en
dc.date.updated 2018-06-20T16:23:22Z
dc.description.version Submitted Version en
dc.internal.rssid 365845672
dc.description.status Peer reviewed en
dc.identifier.journaltitle Journal of computer assisted tomography en
dc.internal.copyrightchecked No !!CORA!! en
dc.internal.licenseacceptance Yes en
dc.internal.IRISemailaddress oj.oconnor@ucc.ie en
dc.internal.IRISemailaddress niamh.moore@ucc.ie en

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