• Placental contribution to the origins of sexual dimorphism in health and diseases: sex chromosomes and epigenetics 

  Junien, Claudine; Gabory, Anne; Rosebool, Tessa J.; Moore, Thomas F.; Moore, Lorna G.; Junien, Claudine (BioMed Central, 2013-03-21)

  Sex differences occur in most non-communicable diseases, including metabolic diseases, hypertension, cardiovascular disease, psychiatric and neurological disorders and cancer. In many cases, the susceptibility to these ...
• Pregnancy-specific glycoproteins bind integrin alpha IIb beta 3 and inhibit the platelet-fibrinogen interaction 

  Shanley, Daniel K.; Kiely, Patrick A.; Golla, Kalyan; Allen, Seamus; Martin, Kenneth; O'Riordan, Ronan T.; Ball, Melanie; Aplin, John D.; Singer, Bernhard B.; Caplice, Noel M.; Moran, Niamh; Moore, Thomas F. (Public Library of Science, 2013)

  Pregnancy-specific glycoproteins (PSGs) are immunoglobulin superfamily members encoded by multigene families in rodents and primates. In human pregnancy, PSGs are secreted by the syncytiotrophoblast, a fetal tissue, and ...
• Site-specific phosphorylation of the DNA damage response mediator Rad9 by cyclin-dependent kinases regulates activation of checkpoint kinase 1 

  Abreu, Carla Manuela; Kumar, Ramesh; Hamilton, Danielle; Dawdy, Andrew William; Creavin, Kevin; Eivers, Sarah; Finn, Karen; Balsbaugh, Jeremy Lynn; O'Connor, Rosemary; Kiely, Patrick A.; Shabanowitz, Jeffrey; Hunt, Donald F.; Grenon, Muriel; Lowndes, Noel Francis (Public Library of Science, 2013)

  The mediators of the DNA damage response (DDR) are highly phosphorylated by kinases that control cell proliferation, but little is known about the role of this regulation. Here we show that cell cycle phosphorylation of ...
• Redox proteomics changes in the fungal pathogen Trichosporon asahii on arsenic exposure: identification of protein responses to metal-induced oxidative stress in an environmentally-sampled isolate 

  Ilyas, Sidra; Rehman, Abdul; Varela, Ana Coelho; Sheehan, David (Public Library of Science, 2014)

  Trichosporon asahii is a yeast pathogen implicated in opportunistic infections. Cultures of an isolate collected from industrial wastewater were exposed for 2 days to 100 mg/L sodium arsenite (NaAsO2) and cadmium (CdCl2). ...
• Transcriptional frameshifting rescues Citrobacter rodentium Type VI secretion by the production of two length variants from the prematurely interrupted tssM gene 

  Gueguen, Erwan; Wills, Norma M.; Atkins, John F.; Cascales, Eric (Public Library of Science, 2014)

  The Type VI secretion system (T6SS) mediates toxin delivery into both eukaryotic and prokaryotic cells. It is composed of a cytoplasmic structure resembling the tail of contractile bacteriophages anchored to the cell ...

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