• A nascent peptide signal responsive to endogenous levels of polyamines acts to stimulate regulatory frameshifting on antizyme mRNA. 

  Yordanova, Martina M.; Wu, Cheng; Andreev, Dmitry E.; Sachs, Matthew S.; Atkins, John F. (American Society for Biochemistry and Molecular Biology, 2015-05-21)

  The protein antizyme is a negative regulator of cellular polyamine concentrations from yeast to mammals. Synthesis of functional antizyme requires programmed +1 ribosomal frameshifting at the 3' end of the first of two ...
• Translational autoregulation of BZW1 and BZW2 expression by modulating the stringency of start codon selection 

  Loughran, Gary; Firth, Andrew E.; Atkins, John F.; Ivanov, Ivaylo P. (Public Library of Science, 2018-02)

  The efficiency of start codon selection during ribosomal scanning in eukaryotic translation initiation is influenced by the context or flanking nucleotides surrounding the AUG codon. The levels of eukaryotic translation ...
• Transcriptional slippage in the positive-sense RNA virus family Potyviridae 

  Olspert, Allan; Chung, Betty Y-W; Atkins, John F.; Carr, John P.; Firth, Andrew E. (EMBO Press, 2015-06-25)

  The family Potyviridae encompasses ~30% of plant viruses and is responsible for significant economic losses worldwide. Recently, a small overlapping coding sequence, termed pipo, was found to be conserved in the genomes ...
• Stop codon readthrough generates a C-terminally extended variant of the human vitamin D receptor with reduced calcitriol response 

  Loughran, Gary; Jungreis, Irwin; Tzani, Ioanna; Power, Michael; Dmitriev, Ruslan I.; Ivanov, Ivaylo P.; Kellis, Manolis; Atkins, John F. (The American Society for Biochemistry and Molecular Biology, Inc., 2018-01-31)

  Although stop codon readthrough is used extensively by viruses to expand their gene expression, verified instances of mammalian readthrough have only recently been uncovered by systems biology and comparative genomics ...
• Systematic analysis of the PTEN 5' leader identifies a major AUU initiated proteoform 

  Tzani, Ioanna; Ivanov, Ivaylo P.; Andreev, Dmitri E.; Dmitriev, Ruslan I.; Dean, Kellie A.; Baranov, Pavel V.; Atkins, John F.; Loughran, Gary (The Royal Society, 2016-05-25)

  Abundant evidence for translation within the 5′ leaders of many human genes is rapidly emerging, especially, because of the advent of ribosome profiling. In most cases, it is believed that the act of translation rather ...

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