• Gut microbiota-mediated bile acid transformations alter the cellular response to multidrug resistant transporter substrates in vitro: focus on P-glycoprotein 

  Enright, Elaine F.; Govindarajan, Kalaimathi; Darrer, Rebecca; MacSharry, John; Joyce, Susan A.; Gahan, Cormac G. (American Chemical Society, ACS, 2018-11-02)

  Pharmacokinetic research at the host-microbe interface has been primarily directed toward effects on drug metabolism, with fewer investigations considering the absorption process. We previously demonstrated that the ...
• Cellulose-based scaffolds for fluorescence lifetime imaging-assisted tissue engineering 

  O'Donnell, Neil; Okkelman, Irina A.; Timashev, Peter; Gromovykh, Tatyana I.; Papkovsky, Dmitri B.; Dmitriev, Ruslan I. (Elsevier Ltd., 2018-09-25)

  Quantitative measurement of pH and metabolite gradients by microscopy is one of the challenges in the production of scaffold-grown organoids and multicellular aggregates. Herein, we used the cellulose-binding domain (CBD) ...
• The GWIPS-viz browser 

  Kiniry, Stephen J.; Michel, Audrey M.; Baranov, Pavel V. (John Wiley & Sons, Inc., 2018-05-16)

  GWIPS-viz is a publicly available browser that provides Genome Wide Information on Protein Synthesis through the visualization of ribosome profiling data. Ribosome profiling (Ribo-seq) is a high-throughput technique which ...
• FES-related tyrosine kinase activates the insulin-like growth factor-1 receptor at sites of cell adhesion 

  Stanicka, Joanna; Rieger, Leonie; O'Shea, Sandra; Cox, Orla; Coleman, Michael; O'Flanagan, Ciara; Addario, Barbara; McCabe, Nuala; Kennedy, Richard; O'Connor, Rosemary (Springer Nature, 2018-03-15)

  IGF-1 receptor (IGF-1R) and integrin cooperative signaling promotes cancer cell survival, proliferation, and motility, but whether this influences cancer progression and therapy responses is largely unknown. Here we ...
• Gold octahedra nanoparticles (Au_0.03 and Au_0.045): Synthesis and impact on marine clams Ruditapes decussatus 

  Fkiri, Anis; Sellami, Badreddine; Selmi, Aymen; Khazri, Abdelhafidh; Saidani, Wiem; Imen, Bouzidi; Sheehan, David; Hamouda, Beyrem; Smiri, Leila Samia (Elsevier, 2018-07-05)

  The increased use of gold nanoparticles (AuNPs) in several applications has led to a rise in concerns about their potential toxicity to aquatic organisms. In addition, toxicity of nanoparticles to aquatic organisms is ...

View more