Bioaccessibility and bioavailability of a marine-derived multimineral, Aquamin-Magnesium

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dc.contributor.author Felice, Valeria D.
dc.contributor.author O'Gorman, Denise M.
dc.contributor.author O'Brien, Nora M.
dc.contributor.author Hyland, Niall P.
dc.date.accessioned 2018-09-27T12:08:19Z
dc.date.available 2018-09-27T12:08:19Z
dc.date.issued 2018
dc.identifier.citation Felice, V., O’Gorman, D., O’Brien, N. and Hyland, N. (2018) 'Bioaccessibility and Bioavailability of a Marine-Derived Multimineral, Aquamin-Magnesium', Nutrients, 10(7), 912 (8pp). doi: 10.3390/nu10070912 en
dc.identifier.volume 10
dc.identifier.issued 7
dc.identifier.startpage 1
dc.identifier.endpage 8
dc.identifier.issn 2072-6643
dc.identifier.uri http://hdl.handle.net/10468/6935
dc.identifier.doi 10.3390/nu10070912
dc.description.abstract Introduction: Magnesium is an essential mineral involved in a range of key biochemical pathways. Several magnesium supplements are present on the market and their degree of bioavailability differs depending on the form of magnesium salt used. Aquamin-Mg is a natural source of magnesium, containing 72 additional trace minerals derived from the clean waters off the Irish coast. However, the in vitro bioaccessibility and bioavailability of Aquamin-Mg in comparison with other supplement sources of magnesium has yet to be tested. Method: Aquamin-Mg, magnesium chloride (MgCl2) and magnesium oxide (MgO) were subjected to gastrointestinal digestion according to the harmonized INFOGEST in vitro digestion method and in vitro bioavailability tested using the Caco-2 cell model. Magnesium concentration was measured by atomic absorption spectrophotometry (AAS). Results: Magnesium recovery from both Aquamin-Mg and MgCl2 was greater than for MgO. Magnesium from all three sources was transported across the epithelial monolayer with Aquamin-Mg displaying a comparable profile to the more bioavailable MgCl2. Conclusions: Our data support that magnesium derived from a marine-derived multimineral product is bioavailable to a significantly greater degree than MgO and displays a similar profile to the more bioavailable MgCl2 and may offer additional health benefits given its multimineral profile. en
dc.description.sponsorship Irish Research Council (Enterprise Partnership Scheme Postdoctoral Fellowship, EPSPD/2015/52); en
dc.format.mimetype application/pdf en
dc.language.iso en en
dc.publisher MDPI AG en
dc.relation.uri http://www.mdpi.com/2072-6643/10/7/912
dc.rights © 2018, the Authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). en
dc.rights.uri http://creativecommons.org/licenses/by/4.0/
dc.subject Aquamin en
dc.subject Multimineral supplement en
dc.subject Magnesium bioavailability en
dc.title Bioaccessibility and bioavailability of a marine-derived multimineral, Aquamin-Magnesium en
dc.type Article (peer-reviewed) en
dc.internal.authorcontactother Nora O'Brien, Food and Nutritional Sciences, University College Cork, Cork, Ireland. +353-21-490-3000 Email: nob@ucc.ie en
dc.internal.availability Full text available en
dc.description.version Published Version en
dc.contributor.funder Marigot Ltd
dc.contributor.funder Irish Research Council
dc.contributor.funder Science Foundation Ireland
dc.description.status Peer reviewed en
dc.identifier.journaltitle Nutrients en
dc.internal.IRISemailaddress nob@ucc.ie en
dc.identifier.articleid 912
dc.relation.project info:eu-repo/grantAgreement/SFI/SFI Research Centres/12/RC/2273/IE/Alimentary Pharmabiotic Centre (APC) - Interfacing Food & Medicine/


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© 2018, the Authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). Except where otherwise noted, this item's license is described as © 2018, the Authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
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