Preventing and Lessening Exacerbations of Asthma in School-aged children Associated with a New Term (PLEASANT): recruiting primary care research sites - the PLEASANT experience

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dc.contributor.author Horspool, Michelle J.
dc.contributor.author Julious, Steven A.
dc.contributor.author Mooney, Cara
dc.contributor.author May, Robin
dc.contributor.author Sully, Ben
dc.contributor.author Smithson, W. Henry
dc.date.accessioned 2018-10-08T08:30:24Z
dc.date.available 2018-10-08T08:30:24Z
dc.date.issued 2015-11-12
dc.identifier.citation Horspool, M. J., Julious, S. A., Mooney, C., May, R., Sully, B. and Smithson, W. H. (2015) 'Preventing and Lessening Exacerbations of Asthma in School-aged children Associated with a New Term (PLEASANT): recruiting primary care research sites - the PLEASANT experience', npj Primary Care Respiratory Medicine, 25, 15066 (5pp). doi:10.1038/npjpcrm.2015.66 en
dc.identifier.volume 25 en
dc.identifier.issn 2055-1010
dc.identifier.uri http://hdl.handle.net/10468/6986
dc.identifier.doi 10.1038/npjpcrm.2015.66
dc.description.abstract Background: Recruitment of general practices and their patients into research studies is frequently reported as a challenge. The Preventing and Lessening Exacerbations of Asthma in School-aged children Associated with a New Term (PLEASANT) trial recruited 142 general practices, across England and Wales and delivered the study intervention to time and target. Aims: To describe the process of recruitment used within the cluster randomised PLEASANT trial and present results on factors that influenced recruitment. Methods: Data were collected on the number of and types of contact used to gain expression of interest and subsequent randomisation into the PLEASANT trial. Practice size and previous research experience were also collected. Results: The mean number of contacts required to gain expression of interest were m=3.01 (s.d. 1.6) and total number of contacts from initial invitation to randomisation m=6.8 (s.d. 3.5). Previous randomised controlled trial involvement (hazard ratio (HR)=1.81 (confidence interval (CI) 95%, 1.55–2.11) P<0.001) and number of studies a practice had previously engaged in (odds ratio (OR) 1.91 (CI 95%, (1.52–2.42)) P<0.001), significantly influenced whether a practice would participate in PLEASANT. Practice size was not a significant deciding factor (OR=1.04 (95% CI 0.99–1.08) P=0.137). Conclusions: Recruitment to time and target can be achieved in general practice. The amount of resource required for site recruitment should not, however, be underestimated and multiple strategies for contacting practices should be considered. General practitioners with more research experience are more likely to participate in studies. en
dc.description.sponsorship National Institute for Health Research (Health Technology Assessment Programme: project number 11/01/10) en
dc.format.mimetype application/pdf en
dc.language.iso en en
dc.publisher Springer Nature Ltd. en
dc.rights © 2015, Primary Care Respiratory Society UK/Macmillan Publishers Limited. This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ en
dc.rights.uri https://creativecommons.org/licenses/by/4.0/ en
dc.subject General practice en
dc.subject Research studies en
dc.subject Trial en
dc.subject Resource en
dc.subject Recruitment en
dc.title Preventing and Lessening Exacerbations of Asthma in School-aged children Associated with a New Term (PLEASANT): recruiting primary care research sites - the PLEASANT experience en
dc.type Article (peer-reviewed) en
dc.internal.authorcontactother William Henry Smithson, General Practice, University College Cork, Cork, Ireland. +353-21-490-3000 Email: henry.smithson@ucc.ie en
dc.internal.availability Full text available en
dc.date.updated 2018-10-05T11:55:55Z
dc.description.version Published Version en
dc.internal.rssid 456735037
dc.contributor.funder National Institute for Health Research en
dc.description.status Peer reviewed en
dc.identifier.journaltitle npj Primary Care Respiratory Medicine en
dc.internal.copyrightchecked Yes en
dc.internal.licenseacceptance Yes en
dc.internal.IRISemailaddress henry.smithson@ucc.ie en
dc.identifier.articleid 15066


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© 2015, Primary Care Respiratory Society UK/Macmillan Publishers Limited. This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ Except where otherwise noted, this item's license is described as © 2015, Primary Care Respiratory Society UK/Macmillan Publishers Limited. This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
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