Preventing and lessening exacerbations of asthma in school-age children associated with a new term (PLEASANT): study protocol for a cluster randomised control trial

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dc.contributor.author Horspool, Michelle J.
dc.contributor.author Julious, Steven A.
dc.contributor.author Boote, Jonathan
dc.contributor.author Bradburn, Mike J.
dc.contributor.author Cooper, Cindy L.
dc.contributor.author Davis, Sarah
dc.contributor.author Elphick, Heather
dc.contributor.author Norman, Paul
dc.contributor.author Smithson, W. Henry
dc.contributor.author vanStaa, Tjeerd
dc.date.accessioned 2018-10-08T08:51:08Z
dc.date.available 2018-10-08T08:51:08Z
dc.date.issued 2013-09-04
dc.identifier.citation Horspool, M. J., Julious, S. A., Boote, J., Bradburn, M. J., Cooper, C. L., Davis, S., Elphick, H., Norman, P., Smithson, W. H. and vanStaa, T. (2013) 'Preventing and lessening exacerbations of asthma in school-age children associated with a new term (PLEASANT): study protocol for a cluster randomised control trial', Trials, 14, 297 (9pp). doi:10.1186/1745-6215-14-297 en
dc.identifier.volume 14 en
dc.identifier.issn 1745-6215
dc.identifier.uri http://hdl.handle.net/10468/6987
dc.identifier.doi 10.1186/1745-6215-14-297
dc.description.abstract Background: Within the UK, during September, there is a pronounced increase in the number of unscheduled medical contacts by school-aged children (4–16 years) with asthma. It is thought that that this might be caused by the return back to school after the summer holidays, suddenly mixing with other children again and picking up viruses which could affect their asthma. There is also a drop in the number of prescriptions administered in August. It is possible therefore that children might not be taking their medication as they should during the summer contributing to them becoming ill when they return to school. It is hoped that a simple intervention from the GP to parents of children with asthma at the start of the summer holiday period, highlighting the importance of maintaining asthma medication can help prevent increased asthma exacerbation, and unscheduled NHS appointments, following return to school in September. Methods/design: PLEASANT is a cluster randomised trial. A total of 140 General Practices (GPs) will be recruited into the trial; 70 GPs randomised to the intervention and 70 control practices of “usual care”. An average practice is expected to have approximately 100 children (aged 4–16 with a diagnosis of asthma) hence observational data will be collected on around 14000 children over a 24-month period. The Clinical Practice Research Datalink will collect all data required for the study which includes diagnostic, prescription and referral data. Discussion: The trial will assess whether the intervention can reduce exacerbation of asthma and unscheduled medical contacts in school-aged children associated with the return to school after the summer holidays. It has the potential to benefit the health and quality of life of children with asthma while also improving the effectiveness of NHS services by reducing NHS use in one of the busiest months of the year. An exploratory health economic analysis will gauge any cost saving associated with the intervention and subsequent impacts on quality of life. If results for the intervention are positive it is hoped that this could be adopted as part of routine care management of childhood asthma in general practice. en
dc.description.sponsorship National Institute for Health Research (Health Technology Assessment (HTA) Programme) en
dc.format.mimetype application/pdf en
dc.language.iso en en
dc.publisher BioMed Central Ltd. en
dc.rights © 2013, Horspool et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. en
dc.rights.uri http://creativecommons.org/licenses/by/2.0
dc.subject Asthma en
dc.subject Childhood asthma en
dc.subject Asthma exacerbation en
dc.subject Cluster randomised controlled trial en
dc.subject Primary care en
dc.subject Public health intervention en
dc.subject Unscheduled medical appointments en
dc.title Preventing and lessening exacerbations of asthma in school-age children associated with a new term (PLEASANT): study protocol for a cluster randomised control trial en
dc.type Article (peer-reviewed) en
dc.internal.authorcontactother William Henry Smithson, General Practice, University College Cork, Cork, Ireland. +353-21-490-3000 Email: henry.smithson@ucc.ie en
dc.internal.availability Full text available en
dc.date.updated 2018-10-08T08:43:34Z
dc.description.version Published Version en
dc.internal.rssid 250594314
dc.contributor.funder National Institute for Health Research en
dc.description.status Peer reviewed en
dc.identifier.journaltitle Trials en
dc.internal.copyrightchecked Yes en
dc.internal.licenseacceptance Yes en
dc.internal.IRISemailaddress henry.smithson@ucc.ie en
dc.identifier.articleid 297


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© 2013, Horspool et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Except where otherwise noted, this item's license is described as © 2013, Horspool et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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