Efficient S-acylation of thiourea
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Date
2018
Authors
Jones, David J.
Khandavilli, Udaya Bhaskara Rao
O'Leary, Eileen M.
Lawrence, Simon E.
O'Sullivan, Timothy P.
Journal Title
Journal ISSN
Volume Title
Publisher
Georg Thieme Verlag
Published Version
Abstract
Efficient S-acylation of thiourea using a variety of acid chlorides is reported. Structurally diverse aryl and alkyl substrates are compatible with this methodology. Confirmation that acylation occurs exclusively on the sulfur atom of thiourea is provided by single-crystal X-ray crystallographic analysis.
Description
Keywords
Isothiourea , Thiourea , Organosulfur , Sulfur transfer
Citation
Jones, D. J., Khandavilli, U. B. R., O’Leary, E. M., Lawrence, S. E. and O’Sullivan, T. P. (2018) 'Efficient S-Acylation of Thiourea', SynOpen, 02(04), pp. 263-267. doi: 10.1055/s-0037-1610370