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dc.contributor.author | Gandhi, Hirenkumar | |
dc.contributor.author | O'Sullivan, Timothy P. | |
dc.date.accessioned | 2018-12-03T14:15:48Z | |
dc.date.available | 2018-12-03T14:15:48Z | |
dc.date.issued | 2017-07-29 | |
dc.identifier.citation | Gandhi, H. and O'Sullivan, T. P. (2017) 'Preparation of γ,δ-unsaturated-β-ketoesters: Lewis acid-catalysed CH insertion of ethyl diazoacetate into α,β-unsaturated aldehydes', Tetrahedron Letters, 58(36), pp. 3533-3535. doi: 10.1016/j.tetlet.2017.07.095 | en |
dc.identifier.volume | 58 | en |
dc.identifier.issued | 36 | en |
dc.identifier.startpage | 3533 | en |
dc.identifier.endpage | 3535 | en |
dc.identifier.issn | 0040-4039 | |
dc.identifier.uri | http://hdl.handle.net/10468/7166 | |
dc.identifier.doi | 10.1016/j.tetlet.2017.07.095 | |
dc.description.abstract | The synthesis of γ,δ-unsaturated-β-keto esters was achieved by the Lewis acid-catalysed direct CH insertion of an α-diazoester into various α,β-substituted-unsaturated aldehydes. CH insertion of ethyl diazoacetate into alkyl- and aryl-substituted α,β-unsaturated aldehydes was performed under mild conditions to afford the corresponding γ,δ-unsaturated-β-keto esters in moderate to high yields as a mixture of keto/enol tautomers. | en |
dc.description.sponsorship | Irish Research Council (Government of Ireland Postgraduate Research Scholarship (GOIPG/2013/113)) | en |
dc.format.mimetype | application/pdf | en |
dc.language.iso | en | en |
dc.publisher | Elsevier | en |
dc.relation.uri | http://www.sciencedirect.com/science/article/pii/S0040403917309644 | |
dc.rights | © 2018 Elsevier Ltd. All rights reserved. This manuscript version is made available under the CC-BY-NC-ND 4.0 license7 | en |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | en |
dc.subject | γ | en |
dc.subject | δ-Unsaturated-β-ketoesters | en |
dc.subject | CH insertion | en |
dc.subject | Ethyl diazoacetate | en |
dc.title | Preparation of γ,δ-unsaturated-β-ketoesters: Lewis acid-catalysed CH insertion of ethyl diazoacetate into α,β-unsaturated aldehydes | en |
dc.type | Article (peer-reviewed) | en |
dc.internal.authorcontactother | Tim O'Sullivan, School Of Pharmacy, University College Cork, Cork, Ireland. +353-21-490-3000 Email: tim.osullivan@ucc.ie | en |
dc.internal.availability | Full text available | en |
dc.check.info | Access to this article is restricted until 24 months after publication by request of the publisher. | en |
dc.check.date | 2019-07-29 | |
dc.date.updated | 2018-11-27T16:53:46Z | |
dc.description.version | Accepted Version | en |
dc.internal.rssid | 413703773 | |
dc.contributor.funder | Irish Research Council![]() |
en |
dc.description.status | Peer reviewed | en |
dc.identifier.journaltitle | Tetrahedron Letters | en |
dc.internal.copyrightchecked | Yes | en |
dc.internal.licenseacceptance | Yes | en |
dc.internal.IRISemailaddress | tim.osullivan@ucc.ie | en |