• Psychobiotics: Evolution of novel antidepressants 

  Dinan, Timothy G.; Butler, Mary I.; Cryan, John F. (S. Karger AG, Basel, 2021)

  The gut-brain axis is a bidirectional communication system which allows the central nervous system and gastrointestinal tract to interact with and respond to each other rapidly and effectively. It is becoming increasingly ...
• Quinacrine and niclosamide promote neurite growth in midbrain dopaminergic neurons through the canonical BMP-Smad pathway and protect against neurotoxin and a-synuclein-induced neurodegeneration 

  Goulding, Susan R.; Lévesque, Martin; Sullivan, Aideen M.; Collins, Louise M.; O'Keeffe, Gerard W. (Springer, 2021-03-12)

  Parkinson's disease is a neurodegenerative disorder characterised by nigrostriatal dopaminergic degeneration, and intracellular a-synuclein aggregation. Current pharmacological treatments are solely symptomatic so there ...
• Of bowels, brain and behavior: A role for the gut microbiota in psychiatric comorbidities in irritable bowel syndrome 

  Wilmes, Lars; Collins, James M.; O'Riordan, Kenneth J.; O'Mahony, Siobhain M.; Cryan, John F.; Clarke, Gerard (John Wiley & Sons, Inc., 2021-02-13)

  Background: The gastrointestinal microbiota has emerged as a key regulator of gut-brain axis signalling with important implications for neurogastroenterology. There is continuous bidirectional communication between the gut ...
• Preeclampsia and neurodevelopmental outcomes: Potential pathogenic roles for inflammation and oxidative stress? 

  Barron, Aaron; McCarthy, Cathal; O'Keeffe, Gerard W. (Springer Nature Switzerland AG, 2021-01-25)

  Preeclampsia (PE) is a common and serious hypertensive disorder of pregnancy that occurs in approximately 3–5% of first-time pregnancies and is a well-known leading cause of maternal and neonatal mortality and morbidity. ...
• Growth differentiation factor 5 exerts neuroprotection in an a-synuclein rat model of Parkinson's disease 

  Goulding, Susan R.; Concannon, Ruth M.; Morales-Prieto, Noelia; Villalobos-Manriquez, Francisca; Clarke, Gerard; Collins, Louise M.; Lévesque, Martin; Wyatt, Sean L.; Sullivan, Aideen M.; O'Keeffe, Gerard W. (Oxford University Press, 2020-11-30)

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