Iron intakes and status of 2-year-old children in the Cork BASELINE Birth Cohort Study

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dc.contributor.author McCarthy, Elaine K.
dc.contributor.author Ní Chaoimh, Carol E.
dc.contributor.author Hourihane, Jonathan O'B.
dc.contributor.author Kenny, Louise C.
dc.contributor.author Irvine, Alan D.
dc.contributor.author Murray, Deirdre M.
dc.contributor.author Kiely, Mairead E.
dc.date.accessioned 2019-02-19T12:21:27Z
dc.date.available 2019-02-19T12:21:27Z
dc.date.issued 2016-08-09
dc.identifier.citation McCarthy, E. K., ní Chaoimh, C., Hourihane, J. O. B., Kenny, L. C., Irvine, A. D., Murray, D. M. and Kiely, M. (2017) 'Iron intakes and status of 2-year-old children in the Cork BASELINE Birth Cohort Study', Maternal & Child Nutrition, 13(3), e12320 (13 pp). doi:10.1111/mcn.12320 en
dc.identifier.volume 13 en
dc.identifier.issued 3 en
dc.identifier.startpage e12320-1 en
dc.identifier.endpage e12320-13 en
dc.identifier.issn 1740-8695
dc.identifier.uri http://hdl.handle.net/10468/7519
dc.identifier.doi 10.1111/mcn.12320
dc.description.abstract Young children are at risk of iron deficiency and subsequent anaemia, resulting in long‐term consequences for cognitive, motor and behavioural development. This study aimed to describe the iron intakes, status and determinants of status in 2‐year‐old children. Data were collected prospectively in the mother–child Cork BASELINE Birth Cohort Study from 15 weeks' gestation throughout early childhood. At the 24‐month assessment, serum ferritin, haemoglobin and mean corpuscular volume were measured, and food/nutrient intake data were collected using a 2‐day weighed food diary. Iron status was assessed in 729 children (median [IQR] age: 2.1 [2.1, 2.2] years) and 468 completed a food diary. From the food diary, mean (SD) iron intakes were 6.8 (2.6) mg/day and 30% had intakes < UK Estimated Average Requirement (5.3 mg/day). Using WHO definitions, iron deficiency was observed in 4.6% (n = 31) and iron deficiency anaemia in five children (1.0%). Following an iron series workup, five more children were diagnosed with iron deficiency anaemia. Twenty‐one per cent had ferritin concentrations <15 µg/L. Inadequate iron intakes (OR [95% CI]: 1.94 [1.09, 3.48]) and unmodified cows' milk intakes ≥ 400 mL/day (1.95 [1.07, 3.56]) increased the risk of low iron status. Iron‐fortified formula consumption was associated with decreased risk (0.21 [0.11, 0.41] P < 0.05). In this, the largest study in toddlers in Europe, a lower prevalence of low iron status was observed than in previous reports. Compliance with dietary recommendations to limit cows' milk intakes in young children and consumption of iron‐fortified products appears to have contributed to improved iron status at two years. en
dc.description.sponsorship National Children’s Research Centre, Ireland (Cork BASELINE Birth Cohort Study); Danone (Danone Nutricia Early Life Nutrition); Health Research Board of Ireland (CSA 02/2007) en
dc.format.mimetype application/pdf en
dc.language.iso en en
dc.publisher Wiley en
dc.relation.uri https://onlinelibrary.wiley.com/doi/abs/10.1111/mcn.12320
dc.rights © 2016 John Wiley & Sons Ltd. This is the peer reviewed version of the following article: McCarthy, E. K., ní Chaoimh, C., Hourihane, J. O. B., Kenny, L. C., Irvine, A. D., Murray, D. M., and Kiely, M. (2017) Iron intakes and status of 2‐year‐old children in the Cork BASELINE Birth Cohort Study. Maternal & Child Nutrition, 13: e12320, which has been published in final form at https://doi.org/10.1111/mcn.12320. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving. en
dc.subject Birth cohort en
dc.subject Iron deficiency en
dc.subject Anaemia en
dc.subject Iron intakes en
dc.subject Food fortification en
dc.subject Cows' milk consumption en
dc.title Iron intakes and status of 2-year-old children in the Cork BASELINE Birth Cohort Study en
dc.type Article (peer-reviewed) en
dc.internal.authorcontactother Elaine McCarthy, Irish Centre for Fetal and Neonatal Translational Research (INFANT), University College Cork, Cork, Ireland. +353-21-490-3000 Email: elaine.mccarthy@ucc.ie en
dc.internal.availability Full text available en
dc.date.updated 2019-02-19T12:10:39Z
dc.description.version Accepted Version en
dc.internal.rssid 474170476
dc.contributor.funder National Children’s Research Centre, Ireland en
dc.contributor.funder Food Standards Agency en
dc.contributor.funder Danone en
dc.contributor.funder Science Foundation Ireland en
dc.description.status Peer reviewed en
dc.identifier.journaltitle Maternal & Child Nutrition en
dc.internal.copyrightchecked No !!CORA!! en
dc.internal.licenseacceptance Yes en
dc.internal.IRISemailaddress m.kiely@ucc.ie en
dc.internal.IRISemailaddress elaine.mccarthy@ucc.ie en
dc.relation.project info:eu-repo/grantAgreement/SFI/SFI Research Centres/12/RC/2272/IE/Irish Centre for Fetal and Neonatal Translational Research (INFANT)/ en


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