Penicillin-binding proteins (PBP) and Lmo0441 (a PBP-like protein) play a role in beta-lactam sensitivity of Listeria monocytogenes

Show simple item record

dc.contributor.author Van de Velde, Sébastien
dc.contributor.author Carryn, Stéphane
dc.contributor.author Van Bambeke, Françoise
dc.contributor.author Hill, Colin
dc.contributor.author Tulkens, Paul M.
dc.contributor.author Sleator, Roy D.
dc.date.accessioned 2012-11-09T08:32:08Z
dc.date.available 2012-11-09T08:32:08Z
dc.date.copyright 2009-12
dc.date.issued 2009-12-15
dc.identifier.citation Van de Velde, S. and Carryn, S. and Van Bambeke, F. and Hill, C. and Tulkens, P.M. and Sleator, R.D. (2009) 'Penicillin-binding Proteins (PBP) and Lmo0441 (a PBP-like protein) play a role in Beta-lactam sensitivity of Listeria monocytogenes'. Gut pathogens, 1:23 doi: 10.1186/1757-4749-1-23 en
dc.identifier.issued 1 en
dc.identifier.startpage 23 en
dc.identifier.issn 1757-4749
dc.identifier.uri http://hdl.handle.net/10468/751
dc.identifier.doi 10.1186/1757-4749-1-23
dc.description.abstract While seven penicillin-binding proteins (PBPs) or PBP-like proteins have been identified either by radiolabelled penicillin binding studies or genomic analysis, only PBP3 has been considered of interest for Beta-lactams activity against Listeria monocytogenes. Herein we reveal that both PBP4 and Lmo0441 (a PBP-like protein) play a direct role in cephalosporin activity in L. monocytogenes while PBP4 additionally has a protective affect against both penicillin and carbapenem. en
dc.description.sponsorship Direction Générale de la Recherche et des Technologies de la Région Wallonne, Belguim (FIRST-Doctorate Fellowship); Science Foundation Ireland (SFI-CSET) en
dc.format.mimetype application/pdf en
dc.language.iso en en
dc.publisher BioMed Central en
dc.relation.uri http://www.gutpathogens.com/content/1/1/23
dc.rights © 2009 Van de Velde et al; licensee BioMed Central Ltd. en
dc.rights.uri http://creativecommons.org/licenses/by/2.0 en
dc.subject Penicillin en
dc.subject Penicillin-Binding en
dc.subject Listeria monocytogenes en
dc.subject Cephalosporin en
dc.subject Carbapenem en
dc.subject Radiolabelled en
dc.title Penicillin-binding proteins (PBP) and Lmo0441 (a PBP-like protein) play a role in beta-lactam sensitivity of Listeria monocytogenes en
dc.type Article (peer-reviewed) en
dc.internal.authorurl http://publish.ucc.ie/researchprofiles/D010/chill en
dc.internal.authorcontactother Colin Hill, Department of Microbiology, University College Cork, Cork, Ireland. Email: c.hill@ucc.ie en
dc.internal.availability Full text available en
dc.description.version Published Version en
dc.internal.rssid 121848281
dc.contributor.funder Direction Générale de la Recherche et des Technologies de la Région Wallonne, Belguim fr
dc.contributor.funder Eumedica SA, Belgium en
dc.contributor.funder Science Foundation Ireland en
dc.contributor.funder Health Research Board en
dc.description.status Peer reviewed en
dc.identifier.journaltitle Gut Pathogens en
dc.internal.IRISemailaddress c.hill@ucc.ie en


Files in this item

This item appears in the following Collection(s)

Show simple item record

© 2009 Van de Velde et al; licensee BioMed Central Ltd. Except where otherwise noted, this item's license is described as © 2009 Van de Velde et al; licensee BioMed Central Ltd.
This website uses cookies. By using this website, you consent to the use of cookies in accordance with the UCC Privacy and Cookies Statement. For more information about cookies and how you can disable them, visit our Privacy and Cookies statement