Towards microbiome-informed dietary recommendations for promoting metabolic and mental health: Opinion papers of the MyNewGut project

Show simple item record

dc.contributor.author Sanz, Yolanda
dc.contributor.author Romaní-Perez, Marina
dc.contributor.author Benítez-Páez, Alfonso
dc.contributor.author Portune, Kevin J.
dc.contributor.author Brigidi, Patrizia
dc.contributor.author Rampelli, Simone
dc.contributor.author Dinan, Timothy G.
dc.contributor.author Stanton, Catherine
dc.contributor.author Delzenne, Nathalie
dc.contributor.author Blachier, François
dc.contributor.author Neyrinck, Audrey M.
dc.contributor.author Beaumont, Martin
dc.contributor.author Olivares, Marta
dc.contributor.author Holzer, Peter
dc.contributor.author Günther, Kathrin
dc.contributor.author Wolters, Maike
dc.contributor.author Ahrens, Wolfgang
dc.contributor.author Claus, Sandrine P.
dc.contributor.author Campoy, Cristina
dc.contributor.author Murphy, Rinki
dc.contributor.author Sadler, Christina
dc.contributor.author Fernández, Laura
dc.contributor.author Kamp, Jan-Willem van der
dc.date.accessioned 2019-06-24T11:49:17Z
dc.date.available 2019-06-24T11:49:17Z
dc.date.issued 2018-12-01
dc.identifier.citation Sanz, Y., Romaní-Perez, M., Benítez-Páez, A., Portune, K.J., Brigidi, P., Rampelli, S., Dinan, T., Stanton, C., Delzenne, N., Blachier, F. and Neyrinck, A.M., 2018. Towards microbiome-informed dietary recommendations for promoting metabolic and mental health: Opinion papers of the MyNewGut project. Clinical nutrition, 37(6), 2191-2199. DOI: 10.1016/j.clnu.2018.07.007 en
dc.identifier.volume 37 en
dc.identifier.issued 6, Part A en
dc.identifier.startpage 2191 en
dc.identifier.endpage 2197 en
dc.identifier.issn 0261-5614
dc.identifier.uri http://hdl.handle.net/10468/8094
dc.identifier.doi 10.1016/j.clnu.2018.07.007 en
dc.description.abstract Summary The gut microbiota coexists in partnership with the human host through adaptations to environmental and physiological changes that help maintain dynamic homeostatic healthy states. Break-down of this delicate balance under sustained exposure to stressors (e.g. unhealthy diets) can, however, contribute to the onset of disease. Diet is a key modifiable environmental factor that modulates the gut microbiota and its metabolic capacities that, in turn, could impact human physiology. On this basis, the diet and the gut microbiota could act as synergistic forces that provide resilience against disease or that speed the progress from health to disease states. Associations between unhealthy dietary patterns, non-communicable diseases and intestinal dysbiosis can be explained by this hypothesis. Translational studies showing that dietary-induced alterations in microbial communities recapitulate some of the pathological features of the original host further support this notion. In this introductory paper by the European project MyNewGut, we briefly summarize the investigations conducted to better understand the role of dietary patterns and food components in metabolic and mental health and the specificities of the microbiome-mediating mechanisms. We also discuss how advances in the understanding of the microbiome's role in dietary health effects can help to provide acceptable scientific grounds on which to base dietary advice for promoting healthy living. en
dc.format.mimetype application/pdf en
dc.language.iso en en
dc.publisher Elsevier en
dc.relation.uri https://www.sciencedirect.com/science/article/pii/S0261561418312093?via%3Dihub
dc.rights © 2018 The Author(s). Published by Elsevier Ltd. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). en
dc.rights.uri https://creativecommons.org/licenses/by/4.0/ en
dc.subject Microbiota en
dc.subject Microbiome en
dc.subject Dietary recommendations en
dc.subject Metabolic health en
dc.subject Mental health en
dc.title Towards microbiome-informed dietary recommendations for promoting metabolic and mental health: Opinion papers of the MyNewGut project en
dc.type Article (peer-reviewed) en
dc.internal.authorcontactother Ted Dinan, APC Microbiome Institute, University College Cork, Cork, Ireland. +353-21-490-3000 Email: T.Dinan@ucc.ie en
dc.internal.availability Full text available en
dc.description.version Published Version en
dc.contributor.funder European Commission en
dc.description.status Peer reviewed en
dc.identifier.journaltitle Clinical Nutrition en
dc.internal.IRISemailaddress t.dinan@ucc.ie en
dc.relation.project info:eu-repo/grantAgreement/EC/FP7::SP1::KBBE/613979/EU/Microbiome Influence on Energy balance and Brain Development-Function Put into Action to Tackle Diet-related Diseases and Behavior./MYNEWGUT en
dc.relation.project info:eu-repo/grantAgreement/EC/FP7::SP3::PEOPLE/609419/EU/MOVE-IN LOUVAIN: Incoming Post-doc Fellowships/MOVE-IN LOUVAIN en


Files in this item

This item appears in the following Collection(s)

Show simple item record

©  2018 The Author(s). Published by Elsevier Ltd. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). Except where otherwise noted, this item's license is described as © 2018 The Author(s). Published by Elsevier Ltd. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
This website uses cookies. By using this website, you consent to the use of cookies in accordance with the UCC Privacy and Cookies Statement. For more information about cookies and how you can disable them, visit our Privacy and Cookies statement