The impact of recent developments in technologies which enable the increased use of biocatalysts
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Date
2019-04-10
Authors
Foley, Aoife M.
Maguire, Anita R.
Journal Title
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Volume Title
Publisher
Wiley
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Abstract
While biocatalytic transformations are very powerful in enantioselective synthesis, frequently occurring under mild conditions, and proceed with extraordinary selectivity, there are practical challenges associated with the use of biocatalysis, such as limited substrate scope, stability, and reusability. Recent technological developments, for example immobilization, continuous flow, and molecular biology, all contribute towards enhancing the use of enzymes in synthesis.
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Keywords
Biocatalysis , Immobilization , Flow chemistry , Molecular biology
Citation
Foley, A. M. and Maguire, A. R. (2019) 'The Impact of Recent Developments in Technologies which Enable the Increased Use of Biocatalysts', European Journal of Organic Chemistry, (23), pp. 3713-3734. doi: 10.1002/ejoc.201900208
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© 2019 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim. This is the peer reviewed version of the following article: Foley, A. M. and Maguire, A. R. (2019), The Impact of Recent Developments in Technologies which Enable the Increased Use of Biocatalysts. Eur. J. Org. Chem., 2019: 3713-3734, which has been published in final form at https://doi.org/10.1002/ejoc.201900208. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.