Small intestinal bacterial overgrowth in children: A state-of-the-art review

Show simple item record

dc.contributor.author Avelar Rodriguez, David
dc.contributor.author Ryan, Paul M.
dc.contributor.author Toro Monjaraz, Erick Manuel
dc.contributor.author Ramirez Mayans, Jaime Alfonso
dc.contributor.author Quigley, Eamonn M.
dc.date.accessioned 2019-10-06T21:39:04Z
dc.date.available 2019-10-06T21:39:04Z
dc.date.issued 2019-09-04
dc.identifier.citation Avelar Rodriguez, D., Ryan, P. M., Toro Monjaraz, E. M., Ramirez Mayans, J. A. and Quigley, E. M. (2019) 'Small Intestinal Bacterial Overgrowth in Children: A State-Of-The-Art Review', Frontiers in Pediatrics, 7, 363 (20pp). DOI: 10.3389/fped.2019.00363 en
dc.identifier.volume 7 en
dc.identifier.startpage 1 en
dc.identifier.endpage 20 en
dc.identifier.uri http://hdl.handle.net/10468/8712
dc.identifier.doi 10.3389/fped.2019.00363 en
dc.description.abstract Small intestinal bacterial overgrowth (SIBO) is a heterogenous and poorly understood entity characterised by an excessive growth of select microorganisms within the small intestine. This excessive bacterial biomass, in turn, disrupts host physiology in a myriad of ways, leading to gastrointestinal and non-gastrointestinal symptoms and complications. SIBO is a common cause of non-specific gastrointestinal symptoms in children, such as chronic abdominal pain, abdominal distention, diarrhoea, and flatulence, amongst others. In addition, it has recently been implicated in the pathophysiology of stunting, a disease that affects millions of children worldwide. Risk factors such as acid-suppressive therapies, alterations in gastrointestinal motility and anatomy, as well as impoverished conditions, have been shown to predispose children to SIBO. SIBO can be diagnosed via culture-dependant or culture-independent approaches. SIBO's epidemiology is limited due to the lack of uniformity and consensus of its diagnostic criteria, as well as the paucity of literature available. Antibiotics remain the first-line treatment option for SIBO, although emerging modalities such as probiotics and diet manipulation could also have a role. Herein, we present a state-of-the-art-review which aims to comprehensively outline the most current information on SIBO in children, with particular emphasis on the gut microbiota. en
dc.format.mimetype application/pdf en
dc.language.iso en en
dc.publisher Frontiers Media en
dc.relation.uri https://www.frontiersin.org/articles/10.3389/fped.2019.00363/full
dc.rights ©2019 Avelar Rodriguez, Ryan, Toro Monjaraz, Ramirez Mayans and Quigley. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. en
dc.rights.uri http://creativecommons.org/licenses/by/4.0/ en
dc.subject Small intestine bacterial overgrowth en
dc.subject Small bowel bacterial overgrowth en
dc.subject Proton pump inhibitors en
dc.subject Gut microbiota en
dc.subject Stunting en
dc.title Small intestinal bacterial overgrowth in children: A state-of-the-art review en
dc.type Article (peer-reviewed) en
dc.internal.authorcontactother Paul MacDaragh Ryan, School of Medicine, University College Cork, Cork, Ireland. +353-21-490-3000. en
dc.internal.availability Full text available en
dc.description.version Published Version en
dc.description.status Peer reviewed en
dc.identifier.journaltitle Frontiers in Pediatrics en
dc.identifier.articleid 363 en
dc.identifier.eissn 2296-2360


Files in this item

This item appears in the following Collection(s)

Show simple item record

©2019 Avelar Rodriguez, Ryan, Toro Monjaraz, Ramirez Mayans and Quigley. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. Except where otherwise noted, this item's license is described as ©2019 Avelar Rodriguez, Ryan, Toro Monjaraz, Ramirez Mayans and Quigley. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
This website uses cookies. By using this website, you consent to the use of cookies in accordance with the UCC Privacy and Cookies Statement. For more information about cookies and how you can disable them, visit our Privacy and Cookies statement