Microstream capnography during conscious sedation with midazolam for oral surgery: a randomised controlled trial.

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dc.contributor.author Brady, Paul
dc.contributor.author Iohom, Gabriella
dc.contributor.author O'Halloran, Ken D.
dc.contributor.author McCreary, Christine
dc.contributor.author Cronin, Michael
dc.date.accessioned 2019-11-29T11:42:23Z
dc.date.available 2019-11-29T11:42:23Z
dc.date.issued 2017-10-11
dc.identifier.citation Brady, P., Iohom, G., O’Halloran, K. D., McCreary, C. and Cronin, M. (2017) 'Microstream capnography during conscious sedation with midazolam for oral surgery: a randomised controlled trial', BDJ Open, 3(1), 17019 (5 pp). doi: 10.1038/bdjopen.2017.19 en
dc.identifier.volume 3 en
dc.identifier.startpage 1 en
dc.identifier.endpage 5 en
dc.identifier.issn 2056-807X
dc.identifier.uri http://hdl.handle.net/10468/9281
dc.identifier.doi 10.1038/bdjopen.2017.19 en
dc.description.abstract Objectives/Aims: There has been no dentistry-specific published data supporting the use of monitoring with capnography for dental sedation. Our aim was to determine if adding capnography to standard monitoring during conscious sedation with midazolam would decrease the incidence of hypoxaemia. Materials and Methods: A randomised controlled trial was conducted in which all patients (ASA I and II) received standard monitoring and capnography, but were randomised to whether staff could view the capnography (intervention) or were blinded to it (control). The primary outcome was the incidence of hypoxaemia (SpO2⩽94%). Results: We enrolled 190 patients, mean age 31 years (range, 14–62 years). There were 93 patients in the capnography group and 97 in the control group. The mean cumulative dose of midazolam titrated was 6.94 mg (s.d., 2.31; range, 3–20 mg). Six (3%) patients, three in each group, required temporary supplemental oxygen. There was no statistically significant difference between the capnography and control groups for the incidence of hypoxaemia: 34.4 vs 39.2% (P=0.4962, OR=0.81, 95% CI: 0.45–1.47). Conclusions: We were unable to confirm an additive role for capnography to prevent hypoxaemia during conscious sedation with midazolam for patients not routinely administered supplemental oxygen. en
dc.description.sponsorship Health Research Board, Ireland (grant number HPF-2013-458 en
dc.format.mimetype application/pdf en
dc.language.iso en en
dc.publisher Springer Nature en
dc.relation.uri https://www.nature.com/articles/bdjopen201719
dc.rights © The Author(s) 2017. This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ en
dc.rights.uri http://creativecommons.org/licenses/by/4.0/ en
dc.subject Sedation en
dc.subject Dental sedation en
dc.subject Capnography en
dc.subject Conscious Sedation en
dc.subject hypoxaemia en
dc.title Microstream capnography during conscious sedation with midazolam for oral surgery: a randomised controlled trial. en
dc.type Article (peer-reviewed) en
dc.internal.authorcontactother Paul Brady, Dental Hospital, University College Cork, Cork, Ireland. +353-21-490-3000 Email: paul.brady@ucc.ie en
dc.internal.availability Full text available en
dc.date.updated 2019-11-28T13:43:40Z
dc.description.version Published Version en
dc.internal.rssid 500042132
dc.internal.pmid 29607089
dc.contributor.funder Health Research Board en
dc.description.status Peer reviewed en
dc.identifier.journaltitle Bdj Open en
dc.internal.copyrightchecked No
dc.internal.licenseacceptance Yes en
dc.internal.IRISemailaddress paul.brady@ucc.ie en
dc.internal.IRISemailaddress giohom@ucc.ie en
dc.internal.IRISemailaddress k.ohalloran@ucc.ie en
dc.internal.IRISemailaddress c.mccreary@ucc.ie en
dc.internal.IRISemailaddress m.cronin@ucc.ie en
dc.identifier.articleid 17019 en


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© The Author(s) 2017. This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ Except where otherwise noted, this item's license is described as © The Author(s) 2017. This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
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