Cork Cancer Research Centre

Cork Cancer Research Centre

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  • Ní Bhuachalla, Éadaoin B.; Daly, Louise E.; Power, Derek G.; Cushen, Samantha J.; MacEneaney, Peter; Ryan, Aoife M. (Wiley Open Access, 2017)
    Background: Nutrition screening on admission to hospital is mandated in many countries, but to date, there is no consensus on which tool is optimal in the oncology setting. Wasting conditions such as cancer cachexia (CC) ...
  • Lehouritis, Panos; Hogan, Glenn; Tangney, Mark (Elsevier, 2017-09-12)
    Bacterial-directed enzyme prodrug therapy (BDEPT) is an emerging form of treatment for cancer. It is a biphasic variant of gene therapy in which a bacterium, armed with an enzyme that can convert an inert prodrug into a ...
  • Murphy, Carola; Rettedal, Elizabeth; Lehouritis, Panos; Devoy, Ciaran; Tangney, Mark (Public Library of Science, 2017)
    Systemic administration of the highly potent anticancer therapeutic, tumour necrosis factor alpha (TNF alpha) induces high levels of toxicity and is responsible for serious side effects. Consequently, tumour targeting is ...
  • Campion, Ciorsdan A.; Soden, Declan; Forde, Patrick F. (BioMed Central, 2016-07-13)
    Background: The ever increasing knowledge in the areas of cell biology, the immune system and the mechanisms of cancer are allowing a new phase of immunotherapy to develop. The aim of cancer vaccination is to activate the ...
  • Falvey, Chloe M.; O'Donovan, Tracey R.; El-Mashad, Shereen M.; Nyhan, Michelle J.; O'Reilly, Seamus; McKenna, Sharon L. (Impact Journals, 2017-02-08)
    Esophageal cancer remains a poor prognosis cancer due to advanced stage of presentation and drug resistant disease. To understand the molecular mechanisms influencing response to chemotherapy, we examined genes that are ...

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