Comparison between different optical systems for optogenetics based head mounted device for retina pigmentosa

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Date
2019-10-07
Authors
Soltan, Ahmed
Liu, Yu
Armstrong, Niall
Akhter, Mahbub
Corbett, Brian
Degenaar, Patrick
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Institute of Electrical and Electronics Engineers (IEEE)
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Abstract
Optogenetics is a fast growing neuromodulation techniques as it can remotely stimulate neural activities of a genetically modified cells. The advantage of remotely controlling the neural activity triggered researchers to implement a headset to externally stimulate retina cells for people with retina pigmentosa. The wearable device requires an efficient optical system to focus the transmitted light pattern into the retina surface. In this work, three different lenses; contact lens, folded prism and linear lenses are used to evaluate the headset performance. A 90x90 μLED display is used as a light source and the optical efficiency for each lens is measured for different points over the lens area. Moreover, the impact of each lens on the headset performance in power and processing will be discussed in this work.
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Keywords
Cellular biophysics , Eye , Genetics , Helmet mounted displays , Lenses , Light emitting diodes , Neurophysiology , Optical prisms , Efficient optical system , Transmitted light pattern , Retina surface , Contact lens , Folded prism , Linear lenses , Headset performance , Light source , Optical efficiency , Lens area , Retina pigmentosa , Neuromodulation techniques , Neural activity , Genetically modified cells , Retina cells , Wearable device , Optogenetics based head mounted device , Headphones , Retina , Optical imaging , Optical distortion , Optical sensors , Optical variables measurement , Optogenetics , Micro-display , Headset , Linear lens , 90x90 μLED display
Citation
Soltan, A., Liu, Y., Armstrong, N., Akhter, M., Corbett, B. and Degenaar, P. (2019) 'Comparison between different optical systems for optogenetics based head mounted device for retina pigmentosa', 2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), Berlin, Germany, 23-27 July, pp. 3820385. doi: 10.1109/EMBC.2019.8857545
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